DRSC/TRiP Functional Genomics Resources

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Protein Alignment: SERPINB6 and Spn88Eb

Sequence 1:XP_011512974.1 Gene:SERPINB6 HGNCID:8950 Length:454 Species:Homo sapiens
Sequence 2:NP_650427.1 Gene:Spn88Eb FlyBaseID:FBgn0038299 Length:426 Species:Drosophila melanogaster

Alignment Length:399 Identity:121/400 (30%)
Similarity:191/400 (48%) Gaps:51/400 (13%)


Human    89 FALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQIL----SFNKSGGGGDIHQ 148
            |:|.|:|.:.: ..|.|:||||.|...||.:.|..:...|..::||.|    :.||         
  Fly    41 FSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNK--------- 96

Human   149 GFQSLLTEVNKTGTQ---------YLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISA 204
              |.:|........|         ..|..|||:|.:::.:..:.|.   ...|.| .:||||.:.
  Fly    97 --QQVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFN---TLLYGA-TKELDFKND 155

Human   205 VEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSK 269
            .|...|.||.|:|:||..:|.::||...:.|.|.|||.||.|.:|.|..||..|.|..:.|.:::
  Fly   156 PETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINE 220

Human   270 NEEKPVQMMFKQSTFKKTYIGEIFTQILVLP----YVGKE-----------LNMIIMLPDET-TD 318
            .|::.|.||.|...||.|....:.:||:.||    |..||           ::|||:||:.. ..
  Fly   221 REQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKIS 285

Human   319 LRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGM 383
            |..|...|..:...:|  .:....:::|:|||:|:.|:..::..:|..:|:...| ...|.|..:
  Fly   286 LNRVISRLNADSVKKW--FERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMF-TRNATFGDL 347

Human   384 SQTDLSL--SKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVP-RFCADHPFLFFIQHSKTNGI 445
            :...:||  ....|.:.::|:|.|:.|||||..::.....:..| :|..:|||:|.|...|.:.|
  Fly   348 TADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTI 412

Human   446 LFCGRFSSP 454
            ||.|.:|.|
  Fly   413 LFAGVYSDP 421

Known Domains:


GeneSequenceDomainRegion External IDIdentity
SERPINB6XP_011512974.1 PAI-2 82..454 CDD:239013 120/398 (30%)
Spn88EbNP_650427.1 SERPIN 37..418 CDD:238101 119/395 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E33208_3BBFJ
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 D556621at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 OOG5_126693
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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