Protein Alignment PHB1 and Phb1

DIOPT Version :10

• Sequence 1: NP_002625.1
• Gene: PHB1 / 5245
• HGNCID: 8912
• Length: 272
• Species: Homo sapiens
• Sequence 2: NP_476607.2
• Gene: Phb1 / 49168
• FlyBaseID: FBgn0002031
• Length: 276
• Species: Drosophila melanogaster
• Alignment Length: 271
• Identity: 204/271 - (75%)
• Similarity: 238/271 - (87%)
• Gaps: 0/271 - (0%)

Human     1 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPI 65
            |||:.|..||:.||.:||.|||||||||||:.||||||||||.|:::.||||||||.|||||:||
  Fly     1 MAAQFFNRIGQMGLGVAVLGGVVNSALYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPI 65

Human    66 IFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSV 130
            |||.||:|||||||||||||||||||||||:||:..|||:|:|.:|:||||||||||..|:||:|
  Fly    66 IFDIRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAV 130

Human   131 VARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAER 195
            ||:|||||||||||:||::||.:||.||..||.||||:||||||||:|||.|||.|||||||||:
  Fly   131 VAQFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEK 195

Human   196 ARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYL 260
            ||||||||||||.|:|||||||::||.|:|.|...|||||:|||::||||||||||||||.:.||
  Fly   196 ARFVVEKAEQQKLASIISAEGDAEAAGLLAKSFGEAGDGLVELRRIEAAEDIAYQLSRSRGVAYL 260

Human   261 PAGQSVLLQLP 271
            |:|||.||.||
  Fly   261 PSGQSTLLNLP 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHB1	NP_002625.1	SPFH_prohibitin	27..221	CDD:259799	150/193 (78%)
Phb1	NP_476607.2	SPFH_prohibitin	27..221	CDD:259799	150/193 (78%)