Protein Alignment PHB1 and CG14736

DIOPT Version :10

• Sequence 1: NP_002625.1
• Gene: PHB1 / 5245
• HGNCID: 8912
• Length: 272
• Species: Homo sapiens
• Sequence 2: NP_731666.2
• Gene: CG14736 / 41466
• FlyBaseID: FBgn0037986
• Length: 473
• Species: Drosophila melanogaster
• Alignment Length: 215
• Identity: 50/215 - (23%)
• Similarity: 99/215 - (46%)
• Gaps: 24/215 - (11%)

Human    51 GEGTHFLIPWVQKPIIFDCRSRPRNV-PVITGSKDLQNVNITLR-ILFRPVASQLPRIFTSIGED 113
            |.|..|::|.:.:....|.|:...|| |....:||  :|.||:. :::..:.|.:..|   |..|
  Fly   103 GPGLVFILPCIDETHRVDMRTDVTNVRPQDVLTKD--SVTITVNAVVYYCIYSPIDSI---IQVD 162

Human   114 YDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKE 178
            ..::....|:...|:::|.......|:|.|:.:||::...:......:|:.::.|.:..:|....
  Fly   163 DAKQATQLISQVTLRNIVGSKTLNVLLTSRQQLSREIQQAVAGITYRWGVRVERVDVMDITLPTS 227

Human   179 FTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELI--ANSLATAGDGLIELRKL 241
            ...::.::..|.:||              :|.||.|||:.||::.:  |:.:.:.....::||.|
  Fly   228 LERSLASEAEAVREA--------------RAKIILAEGELKASKALKEASDVMSENKITLQLRHL 278

Human   242 EAAEDIAYQLSRSRNITYLP 261
            :....||.: .|.|.|..:|
  Fly   279 QILSSIASE-RRVRIIYPIP 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHB1	NP_002625.1	SPFH_prohibitin	27..221	CDD:259799	39/171 (23%)
CG14736	NP_731666.2	SPFH_like	100..305	CDD:473137	50/215 (23%)