Protein Alignment PHB1 and CG31358

DIOPT Version :10

• Sequence 1: NP_002625.1
• Gene: PHB1 / 5245
• HGNCID: 8912
• Length: 272
• Species: Homo sapiens
• Sequence 2: NP_650147.1
• Gene: CG31358 / 41462
• FlyBaseID: FBgn0051358
• Length: 474
• Species: Drosophila melanogaster
• Alignment Length: 248
• Identity: 57/248 - (22%)
• Similarity: 107/248 - (43%)
• Gaps: 48/248 - (19%)

Human    34 HRAVIF--DRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNV-PVITGSKDLQNVNITLR-- 93
            ||.|||  .|.|.    .:|.|..||:|.:......|.|:...|| |....:||  :|:||:.
  Fly    59 HRLVIFRLGRIRS----CLGPGLVFLLPCIDSFNTVDIRTDVVNVDPQEMLTKD--SVSITVNAV 117

Human    94 ---ILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLT 155
               .::.|:.|   .|......|..||    |:...|:::|......||:..|:.:|.::...:.
  Fly   118 VFYCIYDPINS---IIKVDDARDATER----ISQVTLRNIVGSKGLHELLASRQQLSLEIQQAVA 175

Human   156 ERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKA 220
            :....:|:.::.|.|..::.......::.::..|.:||              :|.||.|||::||
  Fly   176 KITERWGVRVERVDLMEISLPSSLERSLASEAEATREA--------------RAKIILAEGEAKA 226

Human   221 AELI--ANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLP 271
            ::.:  .:.:.:.....::||.|:    |...::..|.:       :||..:|
  Fly   227 SKALKECSDVMSENQITLQLRHLQ----ILCSMASERRV-------NVLFPIP 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHB1	NP_002625.1	SPFH_prohibitin	27..221	CDD:259799	48/194 (25%)
CG31358	NP_650147.1	SPFH_like	74..276	CDD:473137	50/229 (22%)