Protein Alignment PHB1 and CG42540

DIOPT Version :10

• Sequence 1: NP_002625.1
• Gene: PHB1 / 5245
• HGNCID: 8912
• Length: 272
• Species: Homo sapiens
• Sequence 2: NP_001246627.1
• Gene: CG42540 / 38562
• FlyBaseID: FBgn0260657
• Length: 517
• Species: Drosophila melanogaster
• Alignment Length: 242
• Identity: 60/242 - (24%)
• Similarity: 107/242 - (44%)
• Gaps: 36/242 - (14%)

Human    35 RAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVP---VITGSKDLQNVNITLRILF 96
            |||||...|.:|....|.|..|::|.:......|.|:|..:||   |:|  ||...|::...:.:
  Fly   218 RAVIFRLGRLMQGGAKGPGIFFILPCIDSYARVDLRTRTYDVPPQEVLT--KDSVTVSVDAVVYY 280

Human    97 RPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATF 161
            | |::....|.......:..|:|...|   |::.:......|::::|..:|..:...|.|....:
  Fly   281 R-VSNATVSIANVENAHHSTRLLAQTT---LRNTMGTRHLHEILSERMTISGTMQVQLDEATDAW 341

Human   162 GLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIAN 226
            |:.::.|.:      |:....|:.::....|||.||        :.:|.:|:|||:.||:..:..
  Fly   342 GIKVERVEI------KDVRLPVQLQRAMAAEAEAAR--------EARAKVIAAEGEQKASRALRE 392

Human   227 SLATAGD--GLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLP 271
            :....||  ..::||.|:....|    |..:|.|       ::..||
  Fly   393 ASEVIGDSPAALQLRYLQTLNTI----SAEKNST-------IVFPLP 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHB1	NP_002625.1	SPFH_prohibitin	27..221	CDD:259799	48/188 (26%)
CG42540	NP_001246627.1	SPFH_stomatin	229..430	CDD:259801	54/231 (23%)