Protein Alignment: PHF7 and pie

• Sequence 1: NP_001308055.1
• Gene: PHF7
• HGNCID: 18458
• Length: 381
• Species: Homo sapiens
• Sequence 2: NP_001260348.1
• Gene: pie
• FlyBaseID: FBgn0005683
• Length: 582
• Species: Drosophila melanogaster
• Alignment Length: 373
• Identity: 110/374 (29%)
• Similarity: 175/374 (47%)
• Gaps: 54/374 (14%)

Human    33 CWLCLREPGDPEKLGEFLQKDNISVHYFCLILSSKLPQRGQSNRGFHGFLPEDIKKEAARASRKI 97
            |.:|.....|....||::...|:.||||||:||:.|||||..:.|..|||..||::|||.|.::.
  Fly     9 CLICKYSDTDDLVFGEWMIVRNLQVHYFCLLLSTHLPQRGGDSSGILGFLLRDIREEAAAAEKRK 73

Human    98 CFVCKKKGAAINCQKDQCLRNFHLPCGQERGCLSQFFGEYKSFCDKHRP----TQNIQHGHVGEE 158
            |:.|.|.||::.|  |:|...|||.||.|...:.:|.|:|||:|.|.||    .:.:|.......
  Fly    74 CWYCNKIGASLQC--DRCRSLFHLKCGLENRAVFEFCGQYKSYCYKCRPMDDYKRQLQSNPPRNA 136

Human   159 SCILCCEDLSQQSVE-NIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNRKEFPQEMLRMGI 222
            :|.:|...:.:..:. .:...||.....|:||:::||.||. ::.:|..|.:.: |...:....:
  Fly   137 TCPICFSSIYKVELHCVVYGDCCRLGFAHKKCMRQYALTSG-YYLRCIWCRSER-FRDSIRLQSV 199

Human   223 HIPDRDAAWELEPGAFSDLYQRYQHCDAPICLYEQGRDSFEDEGRWCLILCATCGSHGTHRDC-- 285
            .:|||||.||.:..|:.:|::|...||.|.||...||.  .:...|.::.|::|.:...|..|
  Fly   200 FVPDRDATWEKQRNAYRELHERNLKCDQPNCLCPSGRT--YNRLSWVILCCSSCAATSAHLKCLV 262

Human   286 SSLRSNSKK----WECEEC---------SPAAATD--------------YIPENSGDIPCCSST- 322
            .:||...|:    ::|..|         .||..|:              |:.:...|....|.|
  Fly   263 GALRLPKKRERTDFKCSMCLDVERRIAEGPARTTEETNADGDNQVDGSFYVQKLGPDAATRSLTQ 327

Human   323 ---FHPEEH----------FCRDNTLEENPGLSWTDWPEPSLLEKPES 357
               |..|:.          |.:..:...:..||.:...|..::|.|:|
  Fly   328 TPVFSEEDESERSSNITVIFSQPKSNATSERLSLSPPQEEMIVEIPDS 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHF7	NP_001308055.1	ePHD_PHF7_G2E3_like	33..144	CDD:277139	50/111 (45%)
		PHD_PHF7_G2E3_like	247..300	CDD:276971	16/59 (27%)
pie	NP_001260348.1	PHD_SF	9..117	CDD:304600	49/110 (45%)
		PHD_SF	224..>260	CDD:304600	11/38 (29%)
		PARM	318..>491	CDD:293666	12/59 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C63786319
eggNOG	1	0.900				E2759_KOG1084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950		0	Normalized mean entropy	S6144
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D110264at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000				T609869
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR12420
Phylome	1	0.910		0.667	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.800