Protein Alignment CSAD and SecS

DIOPT Version :9

• Sequence 1: XP_024304779.1
• Gene: CSAD / 51380
• HGNCID: 18966
• Length: 620
• Species: Homo sapiens
• Sequence 2: NP_649556.3
• Gene: SecS / 40681
• FlyBaseID: FBgn0037347
• Length: 478
• Species: Drosophila melanogaster
• Alignment Length: 531
• Identity: 107/531 - (20%)
• Similarity: 182/531 - (34%)
• Gaps: 159/531 - (29%)

Human   145 PEEL--KQLLDLEL---RSQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHALAGRIIT 204
            ||:|  ...|.|.|   ||:..|.|::||:     |...|.|   :.::....| .|.||
  Fly     9 PEKLVPDNYLQLGLAAQRSKQRSFKELLEK-----RKLPKNG---WSDERIEEL-VHMLA----- 59

Human   205 ESLNTSQYTYEIAPVFVLMEEE--VLRKLRALVGWSSGDGIFCPG----------GS-----ISN 252
             ||:::.|.:::.    |.|.|  :..||.|...::.|.||...|          ||     ::|
  Fly    60 -SLDSNNYPHKVG----LGEREARIACKLVARRHYNFGHGIGRSGDLLEAQPKAAGSTLLARLTN 119

Human   253 MYAVNLARYQRYPDCKQRGLRTLP---PLALFTSKEVGKRHRPNPGLLILISSHVTTPSRRELRF 314
            ...::|.|....|.|  .|...:|   .:.|....:..::.||....::
  Fly   120 ALILDLIRGIGLPSC--AGCFLVPMCTGMTLTLCLQSLRKRRPGARYVL---------------- 166

Human   315 WDLAPTVSEWSRLMREGKWSPRIWRGRLVWPRLRLTFHFFETFILDSGAVPFLVSATSGTTVLGA 379
                     |||:.::..:..                      |..:|.||.::..    .:.|
  Fly   167 ---------WSRIDQKSCFKA----------------------ITATGLVPVVIPC----LIKG- 195

Human   380 FDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRADSVA--------WN-PHKL-L 434
             :.|....|:.:.....|.||     |:|...|..... ..:.:|.:|        |. ||.: .
  Fly   196 -ESLNTNVDLFREKIKSLGVD-----SILCLYTTTSCF-APRNSDDIAEVSKLSKQWQIPHLVNN 253

Human   435 AAGLQCSALLLQ-DTSNLLKRCH--------------GSQASYLFQQDKFYDVALDTGDKVVQCG 484
            |.|||...::.| :.:|.:.|..              ||.....|.:...:|||.....: ....
  Fly   254 AYGLQAKEIVNQLECANRVGRIDYFVQSSDKNLLVPVGSAIVASFNESVLHDVASTYAGR-ASGS 317

Human   485 RRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKK--REGFELVMEPEFVNVCFWFVPPS 547
            :.:|.|...|   :.|..|.....||......||.|.::|  ....|:|::..|.::.......:
  Fly   318 QSLDVLMTLL---SLGRNGFRLLFDQRGENFNYLRENLRKFAEPRGEIVIDSRFNSISLAITLAT 379

Human   548 LRGKQESPDYHERLSKVAPVLKERMVK-------------EGSMMIGYQPHGTRGNF---FRVVV 596
            |.|     |..:.::|:..:|..|.|.             :|...:.:..|  |.|.   :..|.
  Fly   380 LAG-----DQMKSITKLGSMLHMRGVSGARVIVPGQNKTIDGHEFLDFGSH--RSNLQVPYLTVA 437

Human   597 ANSALTCADMD 607
            |...:|..::|
  Fly   438 AGIGITREEID 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSAD	XP_024304779.1	DOPA_deC_like	185..616	CDD:99743	92/486 (19%)
SecS	NP_649556.3	AAT_I	12..457	CDD:302748	105/528 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900