Protein Alignment CSAD and Ddc

DIOPT Version :10

• Sequence 1: XP_054228176.1
• Gene: CSAD / 51380
• HGNCID: 18966
• Length: 652
• Species: Homo sapiens
• Sequence 2: NP_724163.1
• Gene: Ddc / 35190
• FlyBaseID: FBgn0000422
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 268
• Identity: 77/268 - (28%)
• Similarity: 114/268 - (42%)
• Gaps: 37/268 - (13%)

Human   394 GAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRADSV 458
            |.:||....|.|||...|||.|:....|..:|.||:|||||:.||..:...:|||:.||:.|||.
  Fly   267 GLIPFYAVVTLGTTNSCAFDYLDECGPVGNKHNLWIHVDAAYAGSAFICPEYRHLMKGIESADSF 331

Human   459 AWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLFQQDKFY---DV---ALDTGDKVVQCGR 517
            .:||||.:.....|||:.|:|.|.::.         .|..|..|   |:   |.|.....:..||
  Fly   332 NFNPHKWMLVNFDCSAMWLKDPSWVVN---------AFNVDPLYLKHDMQGSAPDYRHWQIPLGR 387

Human   518 RVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVMEPEFVNVCFWFVPPSLRG 582
            |...||||.:.:..|.:.|:..|.:....|:...:.......|||..|.....|||     .|:|
  Fly   388 RFRALKLWFVLRLYGVENLQAHIRRHCNFAKQFGDLCVADSRFELAAEINMGLVCF-----RLKG 447

Human   583 KQESPDYHERLSKVAPVLKERMVK--EGSMMIGYQPHGTRGNFF-RVVVANSALTCADMDFLLNE 644
            ..|.              .|.::|  .|...|...|...:..:| |:.:.:......||::...|
  Fly   448 SNER--------------NEALLKRINGRGHIHLVPAKIKDVYFLRMAICSRFTQSEDMEYSWKE 498

Human   645 LERLGQDL 652
            :.....::
  Fly   499 VSAAADEM 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSAD	XP_054228176.1	DOPA_deC_like	185..648	CDD:99743	77/262 (29%)
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:395219	64/192 (33%)