Protein Alignment CAH16 and CA7

DIOPT Version :10

• Sequence 1: NP_001287620.1
• Gene: CAH16 / 50101
• FlyBaseID: FBgn0040628
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: NP_005173.1
• Gene: CA7 / 766
• HGNCID: 1381
• Length: 264
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 86/278 - (30%)
• Similarity: 125/278 - (44%)
• Gaps: 50/278 - (17%)

  Fly    26 WNYLKNGKD-----WEDL--CSSGKHQSPILLDSRTARKWVLPGITFWHYYRLLKRP-------- 75
            |.|   |:|     |..|  .:.|..||||.:.|..|            .|....:|
Human     7 WGY---GQDDGPSHWHKLYPIAQGDRQSPINIISSQA------------VYSPSLQPLELSYEAC 56

  Fly    76 --FYIRNNGHSISLDIPVTSNGRKPFITGGRLKGRYYADGLHFHWGSYKSRGSEHLINKRRFDAE 138
              ..|.|||||:.:|.  ..:..:..:|||.|:|.|.....|||||.....||||.::.:.|.:|
Human    57 MSLSITNNGHSVQVDF--NDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSE 119

  Fly   139 IHIVHRN-EKYRNIAQAVRQKDGLAVVAIMVAIVRKDNAKSTPLSRLMEAVVRVPIEDSNA--TV 200
            :|:||.| :||....:|....||||||.:.:    :...:...::||.:|:..|..:.:.|  :.
Human   120 LHLVHWNAKKYSTFGEAASAPDGLAVVGVFL----ETGDEHPSMNRLTDALYMVRFKGTKAQFSC 180

  Fly   201 FGQSSLDQLIGGVSHRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSSVSKFWLL----RDHWG 261
            |....|..     :.|.::||.||||||...|:|||||..|...::...:.||..|    .|...
Human   181 FNPKCLLP-----ASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER 240

  Fly   262 HRLINNYRIVQDLNNRTV 279
            ..::||:|..|.|..|.|
Human   241 IHMVNNFRPPQPLKGRVV 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH16	NP_001287620.1	Carb_anhydrase	33..281	CDD:459707	83/271 (31%)
CA7	NP_005173.1	alpha_CA_VII	27..262	CDD:239402	80/255 (31%)