Protein Alignment CAH16 and CA6

DIOPT Version :10

• Sequence 1: NP_001287620.1
• Gene: CAH16 / 50101
• FlyBaseID: FBgn0040628
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: XP_011540386.1
• Gene: CA6 / 765
• HGNCID: 1380
• Length: 324
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 96/293 - (32%)
• Similarity: 138/293 - (47%)
• Gaps: 33/293 - (11%)

  Fly     1 MQAIAFHKLLLLLPLAFYQSTNGMEWNYLKNGKD---WED---LCSSGKHQSPILLDSRTARKW- 58
            |:|:.   |||.|.|...|:.:..:|.|.:...|   |..   .| .|:.||||.| .||..::
Human     5 MRALV---LLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPAC-GGQRQSPINL-QRTKVRYN 64

  Fly    59 -VLPGITFWHYYRLLKRPFYIRNNGHSISLDIPVTSNGRKPFITGGRLKGRYYADGLHFHWGSYK 122
             .|.|:.... |......|.:.||||::.:.:|.|   .:..:..|.:   |.|..:|||||...
Human    65 PSLKGLNMTG-YETQAGEFPMVNNGHTVQISLPST---MRMTVADGTV---YIAQQMHFHWGGAS 122

  Fly   123 SR--GSEHLINKRRFDAEIHIVHRNEKYRNIAQAVRQKDGLAVVAIMVAIVRKDNAKSTPLSRLM 185
            |.  ||||.::..|...||||||.|.||::...|....|||||:|..|.:  |:..::|..|..:
Human   123 SEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEV--KNYPENTYYSNFI 185

  Fly   186 EAVVRVPIEDSNATVFGQSSLDQLIGGVSHRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSSV 250
            ..:..:.......|:.|....|.|...:.|  ::||.||||||.|.|.|.|.|..:...::.:.|
Human   186 SHLANIKYPGQRTTLTGLDVQDMLPRNLQH--YYTYHGSLTTPPCTENVHWFVLADFVKLSRTQV 248

  Fly   251 SKFWLLR----DHWGHRLINNYRIVQDLNNRTV 279
               |.|.    ||....:.|:||..|.||:|.|
Human   249 ---WKLENSLLDHRNKTIHNDYRRTQPLNHRVV 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH16	NP_001287620.1	Carb_anhydrase	33..281	CDD:459707	86/261 (33%)
CA6	XP_011540386.1	alpha_CA_VI	35..283	CDD:239399	86/260 (33%)