Protein Alignment CAH16 and CA10

DIOPT Version :10

• Sequence 1: NP_001287620.1
• Gene: CAH16 / 50101
• FlyBaseID: FBgn0040628
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: NP_064563.1
• Gene: CA10 / 56934
• HGNCID: 1369
• Length: 328
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 78/275 - (28%)
• Similarity: 133/275 - (48%)
• Gaps: 48/275 - (17%)

  Fly    26 WNYLKNGKDWEDLCSSGKHQSPILLDSRTARKWVLPGITFWHYYRLLKRPFYIRNNGHSIS---- 86
            |..:.:.  | :|||.||.|||:.::  |:.....|.:|          |..|...|..:|
Human    50 WGLVNSA--W-NLCSVGKRQSPVNIE--TSHMIFDPFLT----------PLRINTGGRKVSGTMY 99

  Fly    87 ---------LDIPVTSNGRKPFITGGRLKGRYYADGLHFHWGSYKSRGSEHLINKRRFDAEIHIV 142
                     ||.....|     |:||.:...:..:.:..|:||..|:|||||:|.:.|..|:.::
Human   100 NTGRHVSLRLDKEHLVN-----ISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLI 159

  Fly   143 HRN-EKYRNIAQAVRQKDGLAVVAIMVAIVRKDNAKSTP-LSRLM--EAVVRVPIEDSNATVFGQ 203
            |.| |.|.|:.:|.:..:||.||:|.:    |.:..|.| |:|::  :.:.|:..: ::|.:...
Human   160 HYNHELYTNVTEAAKSPNGLVVVSIFI----KVSDSSNPFLNRMLNRDTITRITYK-NDAYLLQG 219

  Fly   204 SSLDQLIGGVSHRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSSVSKFWLLRDHWGHRLI--- 265
            .::::|....|  .|.||:||:|.|.|.||.:||:..:...:|...:....||..:...::.
Human   220 LNIEELYPETS--SFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSM 282

  Fly   266 -NNYRIVQDLNNRTV 279
             :|:|.||.||||.:
Human   283 SDNFRPVQPLNNRCI 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH16	NP_001287620.1	Carb_anhydrase	33..281	CDD:459707	77/268 (29%)
CA10	NP_064563.1	alpha_CARP_X_XI_like	46..302	CDD:239395	78/275 (28%)