Protein Alignment CAH16 and CA13

DIOPT Version :10

• Sequence 1: NP_001287620.1
• Gene: CAH16 / 50101
• FlyBaseID: FBgn0040628
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: NP_940986.1
• Gene: CA13 / 377677
• HGNCID: 14914
• Length: 262
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 83/275 - (30%)
• Similarity: 132/275 - (48%)
• Gaps: 40/275 - (14%)

  Fly    24 MEWNYLK-NGK-DWEDL--CSSGKHQSPILLDSRTARKWVLPGITFWHYYRLLKRPFYIR----- 79
            :.|.|.: ||. .|::.  .:.|..||||.:.::..:            |....||..|:
Human     4 LSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVK------------YDSSLRPLSIKYDPSS 56

  Fly    80 -----NNGHSISLDIPVTSNGRKPFITGGRLKGRYYADGLHFHWGSYKSRGSEHLINKRRFDAEI 139
                 |:|||.::|...|.|  |..:.||.|.|.|....:|.||||....||||:::...:.||:
Human    57 AKIISNSGHSFNVDFDDTEN--KSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAEL 119

  Fly   140 HIVHRN-EKYRNIAQAVRQKDGLAVVAIMVAIVRKDNAKSTPLSRLMEAVVRVPIEDSNATVFGQ 203
            |:||.| :||.:..:|..:.|||||:.:.:.| .:.|::...::..::::.    |....|.|..
Human   120 HVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQI-GEPNSQLQKITDTLDSIK----EKGKQTRFTN 179

  Fly   204 SSLDQLIGGVSHRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSSVSKF-WLLRDHWGHR---L 264
            ..|..|:  ....|::||.||||.|...|:|||||..:...::...::|| .||....|..   |
Human   180 FDLLSLL--PPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFL 242

  Fly   265 INNYRIVQDLNNRTV 279
            ::|:|..|.|..|.|
Human   243 VSNHRPPQPLKGRKV 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH16	NP_001287620.1	Carb_anhydrase	33..281	CDD:459707	79/265 (30%)
CA13	NP_940986.1	alpha_CA_I_II_III_XIII	2..261	CDD:239393	83/275 (30%)