Protein Alignment CAH16 and CA14

DIOPT Version :10

• Sequence 1: NP_001287620.1
• Gene: CAH16 / 50101
• FlyBaseID: FBgn0040628
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: NP_036245.1
• Gene: CA14 / 23632
• HGNCID: 1372
• Length: 337
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 94/286 - (32%)
• Similarity: 136/286 - (47%)
• Gaps: 31/286 - (10%)

  Fly    10 LLLLPLAFYQSTNGMEWNYL-KNGKD-WE---DLCSSGKHQSPILL--DSRTARKWVLPGITFWH 67
            |||..:....:..|..|.|. .:|:| |.   ..|.:.. ||||.:  ||.|... .||.:....
Human     6 LLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNA-QSPIDIQTDSVTFDP-DLPALQPHG 68

  Fly    68 YYRLLKRPFYIRNNGHSISLDIPVTSNGRKPFITGGRLKGRYYADGLHFHWGSYKS-RGSEHLIN 131
            |.:....|..:.||||::.|.:|.|      ...|| |..:|.|..||.|||...| .||||.||
Human    69 YDQPGTEPLDLHNNGHTVQLSLPST------LYLGG-LPRKYVAAQLHLHWGQKGSPGGSEHQIN 126

  Fly   132 KRRFDAEIHIVH-RNEKYRNIAQAVRQKDGLAVVAIMVAIVRKDN-AKSTPLSRLMEAVVRVPIE 194
            .....||:|||| .::.|.::::|..:..||||:.|::.:....| |....||.|.|  ||...:
Human   127 SEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHE--VRHKDQ 189

  Fly   195 DSNATVFG-QSSLDQLIGGVSHRDFFTYEGSLTTPLCDETVTWIVFTETTTVTMSSVSK----FW 254
            .::...|. :..|.:.:|     .:|.|.||||||.|.::|.|.||...:.::|..:.|    .:
Human   190 KTSVPPFNLRELLPKQLG-----QYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLF 249

  Fly   255 LLRDHWGHRLINNYRIVQDLNNRTVF 280
            ...:.....|:.|||.:|.||.|.||
Human   250 STEEEPSKLLVQNYRALQPLNQRMVF 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH16	NP_001287620.1	Carb_anhydrase	33..281	CDD:459707	87/262 (33%)
CA14	NP_036245.1	alpha_CA_XII_XIV	29..278	CDD:239400	88/263 (33%)