DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15864 and P4htm

DIOPT Version :9

Sequence 1:	NP_652183.2	Gene:	CG15864 / 50001	FlyBaseID:	FBgn0040528	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_083220.3	Gene:	P4htm / 74443	MGIID:	1921693	Length:	503	Species:	Mus musculus

Alignment Length:	226	Identity:	65/226 - (28%)
Similarity:	95/226 - (42%)	Gaps:	65/226 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 DTEIDGMLNSSNF-GLSLTD-----SGQKSE----VRTSKDSYIVDA-------KTLNERVTDMT 358
            |.:.||:|:...| .:.|.|     ...|:|    ||.|..:::...       :.:.:||..:|
Mouse   238 DPDGDGVLSLQEFSNMDLRDFHKYMRSHKAESNELVRNSHHTWLHQGEGAHHVMRAIRQRVLRLT 302

  Fly   359 GFS---MEMSDPFSLINYGLGGHYMLHYD----FHE--------YTNTTRP-KQGDRIATVLFYL 407
            ..|   :|.|:|..::.||.||||..|.|    :.|        ..|.:.| :...|..||||||
Mouse   303 RLSPEIVEFSEPLQVVRYGEGGHYHAHVDSGPVYPETICSHTKLVANESVPFETSCRYMTVLFYL 367

  Fly   408 GEVDSGGATIFPMI---------------------------NITVTPKKGSAVFWYNLHNS---- 441
            ..|..||.|:||:.                           |:.|.|::|:||||||....
Mouse   368 NNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGW 432

  Fly   442 -GAMNLKSLHSACPVISGSKYVLTKWINELP 471
             |.::..|||..|.|..|:|::...|||..|
Mouse   433 VGEVDDYSLHGGCLVTRGTKWIANNWINVDP 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15864	NP_652183.2	P4Ha_N	35..166	CDD:285528
		metallo-dependent_hydrolases	<237..>306	CDD:294200
		P4Hc	313..467	CDD:214780	60/218 (28%)
P4htm	NP_083220.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	90..110
		EF-hand_7	193..253	CDD:290234	5/14 (36%)
		EFh	195..253	CDD:298682	5/14 (36%)
		P4Hc	247..459	CDD:214780	57/211 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839371
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740