Protein Alignment CG15864 and P4ha1

DIOPT Version :10

• Sequence 1: NP_652183.2
• Gene: CG15864 / 50001
• FlyBaseID: FBgn0040528
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_742059.2
• Gene: P4ha1 / 64475
• RGDID: 621000
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 518
• Identity: 146/518 - (28%)
• Similarity: 245/518 - (47%)
• Gaps: 81/518 - (15%)

  Fly    32 YAASTMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKSDYESYLGNPLNSF 96
            :..|..::..|:..|.:||.:||.|:|..:.|...:::....:.|.......|.|.::|:|:|:|
  Rat    21 FFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAF 85

  Fly    97 RLIHRLHTSWRKWYQYAIKVENNALGHIENARLMRKMLPTSSDLQQACRGIHDLMSFYDLKPEEL 161
            :|:.||:|.|.:.....:|..::  |.|.|..:.|:..|...|...|.:.:..|...|:|....:
  Rat    86 KLMKRLNTEWSELENLILKDMSD--GFISNLTIQRQYFPNDEDQVGAAKALFRLQDTYNLDTNTI 148

  Fly   162 AAGNLAGYSQPGTGLTAYDCLALGEFSVQKREDDLAEAWYNLSLIRFE----NKFDK-------- 214
            :.|||.|.... :.|||.||..||:.:..:.:....|.|...:|::.|    :..||
  Rat   149 SKGNLPGVKHK-SFLTAEDCFELGKVAYTEADYYHTELWMEQALMQLEEGEMSTVDKVSVLDYLS 212

  Fly   215 YRVHKAWGL---LLAKNKQLTDAFYHFENKPEGIIASNEVIHFK------------------EEL 258
            |.|::...|   ||...|.|       |..||...|:..:::|:                  ::.
  Rat   213 YAVYQQGDLDKALLLTKKLL-------ELDPEHQRANGNLVYFEYIMSKEKDANKSASGDQSDQK 270

  Fly   259 STKQNCAVVV----------------------QKPSRLHCRYNT-TTTPFTRIAPLKMEELGLDP 300
            :|.:...:.|                      ::..||.|||:. ...|...:||.|.|:....|
  Rat   271 TTPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKP 335

  Fly   301 YMVVFHDVIYDTEIDGMLNSSNFGLSLT-----DSGQ--KSEVRTSKDSYIVD-----AKTLNER 353
            .::.|||:|.|.||:.:.:.:...||..     ::|:  .::.|.||.:::..     ...:|.|
  Rat   336 RIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYEDPVVSRINMR 400

  Fly   354 VTDMTGFSMEMSDPFSLINYGLGGHYMLHYDFHEYTNTTRPKQ---GDRIATVLFYLGEVDSGGA 415
            :.|:||..:..::...:.|||:||.|..|:||.........::   |:||||.|||:.:|.:|||
  Rat   401 IQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGA 465

  Fly   416 TIFPMINITVTPKKGSAVFWYNLHNSGAMNLKSLHSACPVISGSKYVLTKWINELPQMFVTPC 478
            |:||.:..:|.||||:|||||||..||..:..:.|:||||:.|:|:|..||::|..|.|..||
  Rat   466 TVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPC 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15864	NP_652183.2	P4Ha_N	35..168	CDD:462433	36/132 (27%)
		P4Hc	313..467	CDD:214780	60/168 (36%)
P4ha1	NP_742059.2	P4Ha_N	24..155	CDD:462433	36/132 (27%)
		TPR	205..238		9/39 (23%)
		P4Hc	345..518	CDD:214780	62/172 (36%)