Protein Alignment CG15864 and p4ha2

DIOPT Version :10

• Sequence 1: NP_652183.2
• Gene: CG15864 / 50001
• FlyBaseID: FBgn0040528
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: XP_012814344.2
• Gene: p4ha2 / 493342
• XenbaseID: XB-GENE-957618
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 521
• Identity: 139/521 - (26%)
• Similarity: 237/521 - (45%)
• Gaps: 92/521 - (17%)

  Fly    35 STMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKSDYESYLGNPLNSFRLI 99
            ||.::..|:..|.:|:.:||.|::..:.:.:.::|...::...:....:|.|.|||:|:|:::|:
 Frog    26 STGQMTDLIFRERDLLQSLKEYIREEEERLSKIKRWASEVDELSSRSTADPEGYLGHPVNAYKLV 90

  Fly   100 HRLHTSWRKWYQYAIKVENNALGHIENARLMRKMLPTSSDLQQACRGIHDLMSFYDLKPEELAAG 164
            .|.:|.|.....  :.::::|.|.|.|....|:..||..|...|.|.:..:...|.|.|:.:|.|
 Frog    91 KRFNTDWSSLEN--LVLQDSAKGFIANFTFQREYFPTEEDETGAARALMRIQDTYKLDPDVIAKG 153

  Fly   165 NLAGYSQPGT----GLTAYDCLALGEFSVQKREDDLAEAWYNLSLIRFE-------NKFD----- 213
            .|     |||    .|:|.|...:|:.:....:......|...:|.:.:       ||.|
 Frog   154 KL-----PGTNYISSLSADDSFGMGKIAYHDGDYYHTVLWMQQALKQMDEGEDAVVNKVDVLDYL 213

  Fly   214 KYRVHKAW----GLLLAKNKQLTDA-----------FYHFENKPEGIIASNEVIHFK-------- 255
            .|.|.:..    .|.|.|.....|.           |...:.|.:..:..||..:.:
 Frog   214 SYTVFQLGDVPRALELTKRLLALDPNHDRAVNNLKYFEKMQEKQKAELKQNESTNTESATRQPGV 278

  Fly   256 --------------EELSTKQNCAVVVQKPSRLHCRY-NTTTTPFTRIAPLKMEELGLDPYMVVF 305
                          |.|...:...:..::..||.||| |...:|:..::|:|:|:....|.:|.:
 Frog   279 YSRPLDYLPERDVYEALCRGEGVKMNPRRQRRLFCRYHNGNRSPYLILSPVKVEDEWDSPRIVRY 343

  Fly   306 HDVIYDTEI--------------------DGMLNSSNFGLSLTDSGQKSEVRTSKDSYIVDAKTL 350
            .:.:.|.||                    .|:|:.:|:.:|      ||......|..::  ..:
 Frog   344 LNALSDEEIAKIKELAKPKLARATVRDPKTGVLSVANYRVS------KSAWLEENDDPVI--ARV 400

  Fly   351 NERVTDMTGFSMEMSDPFSLINYGLGGHYMLHYDF---HEYTNTTRPKQGDRIATVLFYLGEVDS 412
            |.|:..:||.:::.::...:.|||:||.|..|:||   .|.....|...|:|:||.|.|:.:|::
 Frog   401 NLRMQAITGLTVDTAELLQVANYGMGGQYEPHFDFSRKDEPDVFKRLGTGNRVATFLNYMSDVEA 465

  Fly   413 GGATIFPMINITVTPKKGSAVFWYNLHNSGAMNLKSLHSACPVISGSKYVLTKWINELPQMFVTP 477
            ||||:||.....:.||||:|||||||..||..:.::.|:||||:.|||:|..||.:|..|.|:.|
 Frog   466 GGATVFPDFGAAIWPKKGTAVFWYNLFRSGEGDYRTRHAACPVLVGSKWVSNKWFHERGQEFLRP 530

  Fly   478 C 478
            |
 Frog   531 C 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15864	NP_652183.2	P4Ha_N	35..168	CDD:462433	36/132 (27%)
		P4Hc	313..467	CDD:214780	60/176 (34%)
p4ha2	XP_012814344.2	P4Ha_N	26..157	CDD:462433	36/137 (26%)
		BepA	166..>247	CDD:443813	14/80 (18%)
		TPR repeat	166..201	CDD:276809	5/34 (15%)
		TPR repeat	206..236	CDD:276809	7/29 (24%)
		P4Hc	348..521	CDD:214780	62/180 (34%)