DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15864 and CG34041

DIOPT Version :9

Sequence 1:	NP_652183.2	Gene:	CG15864 / 50001	FlyBaseID:	FBgn0040528	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster

Alignment Length:	349	Identity:	74/349 - (21%)
Similarity:	160/349 - (45%)	Gaps:	70/349 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 SACFINCQGFV-----KSNPKKSYAASTMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLID 73
            |||.::. |.:     .||.:..::.|..:::.:|::::.:|..|:.|:..|:.|...::.:|||
  Fly   235 SACILSV-GLIIVYLSYSNSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTIDEALID 298

  Fly    74 MSRENMEMKSDYESYLGNPLNSFRLIHRLHTSWRKWYQYAIKVENNALGHIENARLM--RKMLPT 136
            ::..:::.:.|..:...:|:.|:.|||.:.:.|..|..:.    ....|..|.|.||  :|.|||
  Fly   299 LATYHIQFERDKLAIASSPVASYSLIHHMQSDWTHWQLFL----QEDPGKDELASLMSIKKYLPT 359

  Fly   137 SSDLQQACRGIHDLMSFYDLKPEELAAGNLAG----YSQPGTGL--------------TAYDCLA 183
            .:|:.:.|.||..:::.|.:..:::|.|.:.|    |......|              :..||:|
  Fly   360 KNDISEVCHGISKMLNAYLMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVA 424

  Fly   184 LGEFSVQKREDDLAEAWYNLSLIRFENK----------------FDKYRVHKAWGLLLAKNKQLT 232
            |.:.|::.::.:.::.|.|:::...|:.                .:.|...:.|.|.|...:
  Fly   425 LSDHSMEMKDYNKSKEWLNVAISMLESSAYWDPIVPSADLYLKLAEVYVKQQNWTLALETVE--- 486

  Fly   233 DAFYHFENKPEGIIASNEVIHFKEELS-------------TKQNCAVVVQKPSRLHCRYNT-TTT 283
               :..::.|.    :.::|..::.||             ..:|....::|...|:|.|:| ..|
  Fly   487 ---FALKSNPR----NAQLIRMQKRLSYHILLGPPKSPKLNIENNDYRLRKNGSLYCFYDTKIRT 544

  Fly   284 PFTRIAPLKMEELGLDPYMVVFHD 307
            .::.:||:|.|.|.:||.::::|:
  Fly   545 FYSLLAPIKAEVLFIDPLVILYHE 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15864	NP_652183.2	P4Ha_N	35..166	CDD:285528	34/132 (26%)
		metallo-dependent_hydrolases	<237..>306	CDD:294200	18/82 (22%)
		P4Hc	313..467	CDD:214780
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	34/132 (26%)
		TPR repeat	452..491	CDD:276809	4/44 (9%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461981
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840