Protein Alignment CG15864 and dpy-18

DIOPT Version :10

• Sequence 1: NP_652183.2
• Gene: CG15864 / 50001
• FlyBaseID: FBgn0040528
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_499464.1
• Gene: dpy-18 / 176569
• WormBaseID: WBGene00001077
• Length: 559
• Species: Caenorhabditis elegans
• Alignment Length: 519
• Identity: 140/519 - (26%)
• Similarity: 235/519 - (45%)
• Gaps: 82/519 - (15%)

  Fly    35 STMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKSDYESYLGNPLNSFRLI 99
            |..::..|||.|..:...|..|:...:.:...:::...:.|::|.....:....:.||:|:|.||
 Worm    21 SIADMQNLLETERNIPKILDKYIHDEEERLVQLKKLSEEYSKKNEISIENGLKDITNPINAFLLI 85

  Fly   100 HRLHTSWRKWYQYAIKVENNALGHI-----ENARLMRKMLPTSSDLQQACRGIHDLMSFYDLKPE 159
            .|....|:   :...|:..|..|::     :::..:|  .||:.||..|..|:..|...|.|..:
 Worm    86 KRKIFDWK---EIESKMNANKAGNVVSSITDDSYGVR--YPTADDLSGAAIGLLRLQDTYRLDTK 145

  Fly   160 ELAAGNLAGYSQPGT-GLTAYDCLALGEFS---------------VQKREDD------------- 195
            :||.|.:  |:..|. ..:|.||..:...:               .|:|..|
 Worm   146 DLADGKI--YADQGNYTFSAKDCFEIARAAYNEHDFYHTVMWMEEAQRRLGDEVEPTVEVEDILE 208

  Fly   196 -LAEAWYNLSLIRFENKF--DKYRVHKA---------W--GLLLAKNKQLTDAFYHF----ENKP 242
             ||.|.|..:.::...|.  :.|:::..         |  .||..:..:.:|...:.    ..:|
 Worm   209 YLAFALYKQNNLKHALKLTEELYKMNPTHPRAKGNVKWYEDLLEQEGVRRSDMRKNLPPIQNRRP 273

  Fly   243 EGIIASNEVIHFKEELSTKQNCAVVVQKP-SRLHCRYNTTTTPFTRIAPLKMEELGLDPYMVVFH 306
            :.::.:.|...::   :..:|...|.||. |||:|.|. ...||...||:|:|....:|..|:|.
 Worm   274 DSVLGNTERTMYE---ALCRNEVPVSQKDISRLYCYYK-RDRPFLVYAPIKVEIKRFNPLAVLFK 334

  Fly   307 DVIYDTEIDGM-------LNSSNFGLSLTDSGQKSEVRTSKDSYIVD-----AKTLNERVTDMTG 359
            |||.|.|:..:       |..:....|:|.....:..|.||.:::.:     .:|:|:|:..||.
 Worm   335 DVISDDEVAAIQELAKPKLARATVHDSVTGKLVTATYRISKSAWLKEWEGDVVETVNKRIGYMTN 399

  Fly   360 FSMEMSDPFSLINYGLGGHYMLHYDFHEYTNTTRPKQ----GDRIATVLFYLGEVDSGGATIFPM 420
            ..||.::...:.|||:||||..|:| |.....::..:    |:||||||||:.:...||.|:|..
 Worm   400 LEMETAEELQIANYGIGGHYDPHFD-HAKKEESKSFESLGTGNRIATVLFYMSQPSHGGGTVFTE 463

  Fly   421 INITVTPKKGSAVFWYNLHNSGAMNLKSLHSACPVISGSKYVLTKWINELPQMFVTPC-MKDSN 483
            ...|:.|.|..|:|||||:..|..|..:.|:||||:.|.|:|..|||:|....|..|| :|.|:
 Worm   464 AKSTILPTKNDALFWYNLYKQGDGNPDTRHAACPVLVGIKWVSNKWIHEKGNEFRRPCGLKSSD 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15864	NP_652183.2	P4Ha_N	35..168	CDD:462433	33/137 (24%)
		P4Hc	313..467	CDD:214780	57/169 (34%)
dpy-18	NP_499464.1	P4Ha_N	21..152	CDD:462433	33/135 (24%)
		NrfG	150..>240	CDD:443378	15/91 (16%)
		P4Hc	338..511	CDD:214780	59/173 (34%)