DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alpha-Catr and Vinac1

DIOPT Version :9

Sequence 1:	NP_726389.4	Gene:	alpha-Catr / 49713	FlyBaseID:	FBgn0029105	Length:	810	Species:	Drosophila melanogaster
Sequence 2:	NP_001357870.1	Gene:	Vinac1 / 668894	MGIID:	3649276	Length:	1413	Species:	Mus musculus

Alignment Length:	218	Identity:	44/218 - (20%)
Similarity:	93/218 - (42%)	Gaps:	21/218 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 RDMDNEQIMSTFGNIGHLLNIAVERFITIGEIIAEENID--IKGDMYEAAKEARDAGKSIERLCD 79
            :::.|:.:.| ...:...|..|.|.|:.:...:|.::.:  ::.:|...|:....:|::|.|:.:
Mouse    41 KEVQNKALAS-LQKVAEQLANASEEFVHVASRLAGDSEEKWLREEMKPVAESLILSGRNILRVAE 104

  Fly    80 ISPLSGMELRHHIEP--LKDYGAIILAARSLLSSVTRILLLVDIIVVKKLLTAKKRASESLEKLE 142
                     :.|::|  .:.:..::..|:.:|....::|||.|...|:|..||.......:|.||
Mouse   105 ---------KLHLQPESQRHWEELVATAQQVLVDTKKVLLLDDAAAVRKTRTAANWCLTCVEALE 160

  Fly   143 SVMNFTEFVRAFSVFGTEMIELAYLTGHHRNSFKEERRRAQMFSARQILEKSIAILLTSSKNSLI 207
            ...:.|....:.......:..|..||.  |.::.:...|     ||..|...:..||.::...|.
Mouse   161 EAEDTTSLRTSLDDLAAALFRLGGLTA--RWAWDQHLGR-----ARHRLGCCVPALLAAAHGHLR 218

  Fly   208 HSDCVIVKENRDTVFCQIRRAMD 230
            |.....:..:|..||...|::::
Mouse   219 HPRDPQLVASRRRVFALTRQSLE 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Catr	NP_726389.4	Vinculin	52..755	CDD:279395	37/183 (20%)
Vinac1	NP_001357870.1	Vinculin	15..>610	CDD:366435	44/218 (20%)
Vinac1	NP_001357870.1	Vinculin	<1224..1375	CDD:366435
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3681
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810