Protein Alignment alpha-Catr and ctnna2

DIOPT Version :10

• Sequence 1: NP_726389.4
• Gene: alpha-Catr / 49713
• FlyBaseID: FBgn0029105
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: XP_005160129.1
• Gene: ctnna2 / 567500
• ZFINID: ZDB-GENE-060815-3
• Length: 905
• Species: Danio rerio
• Alignment Length: 863
• Identity: 186/863 - (21%)
• Similarity: 337/863 - (39%)
• Gaps: 221/863 - (25%)

  Fly    33 HLLNIAVER----FITIGEIIAEENIDIKGDMYEAAKEARDAGKSI----ERLCDISPLSGMELR 89
            |:|.::||:    |:..||.||:::.|:|.::..|.::.|..|.::    ....| .|.|.::
Zfish    58 HVLAVSVEQATQNFLEKGEQIAKDSQDLKEELIAAVEDVRKQGDTMRVASSEFAD-DPCSSVK-- 119

  Fly    90 HHIEPLKDYGAIILAARSLLSSVTRILLLVDIIVVKKLLTAKKRASESLEKLESVMNFTEFVRAF 154
                    .|.::.|||:|||:|||:|:|.|:..|.:||...|...|:||.:::..|..:....|
Zfish   120 --------RGTMVRAARALLSAVTRLLILADMADVMRLLAHLKIVEEALEAVKNATNEQDLANRF 176

  Fly   155 SVFGTEMIELAYLTGHHRNSFKEERRRAQMFSARQILEKSIAILLTSSKNSLIHSDCVIVKENRD 219
            ..||.||::|.|:....:...|:.:.|.:|.:||..|:|:..:|.|:|:..|.|.|....:.|||
Zfish   177 KEFGKEMVKLNYVAARRQQELKDPQCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRD 241

  Fly   220 TVFCQIRRAMDLIHFVVKDSIFDTAKHMPFEKQASNPNYENESIYTTIKRIVNLIKRYKYQMSYY 284
            .||.|::.|:        ..|..:|       ||::|..|...                     :
Zfish   242 YVFKQVQEAI--------GGISSSA-------QATSPTDEKHG---------------------H 270

  Fly   285 EGSGE---GNNNSDAYFSFLDDDLWKS--------EKNLPSAAGGGRMVNNTNF-----RKHLSS 333
            .|.||   ..|..|.  ..:.|.|..|        |:.|.|...|..::.:::.     |:.:.:
Zfish   271 AGIGELAAALNEFDN--KIILDPLTFSEARFRPSLEERLESIISGAALMADSSCTRDDRRERIVA 333

  Fly   334 ESLDLR--------------------EELSLAFEKLFEKAHDFTDSPYISHNHRKNILSYCDNCK 378
            |...:|                    :.|:.|.:|:.:|..|      :....||.::.:..:..
Zfish   334 ECNAVRQALQDLLSEYMNNTGRKEKGDPLNSAIDKMTKKTRD------LRRQLRKAVMDHISDSF 392

  Fly   379 LEFDLYLNTIMKDQHEGGGGAGGVGGVGGGQVK---------------------GRSDPELGM-- 420
            ||.::.|..:::....|          ...:||                     ..|:.|.|:
Zfish   393 LETNVPLLVLIEAAKSG----------NEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKL 447

  Fly   421 ----LSSLEELCKQLV------------------------------------VSVSSQIEDF--- 442
                .:.::.||.|::                                    |...:.::||
Zfish   448 VRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVRILTEAVDDITSVDDFLSV 512

  Fly   443 --NESLKICSKLVKSFHVLATNYDIDNLNQRSSKFHDCCDHIFDICKL-LQHIAP---TERLQVQ 501
              |..|:..:|.|    :.....|:|.|::.:.........:..|... :::..|   |||:...
Zfish   513 SENHILEDVNKCV----IALQEGDVDTLDRTAGAIRGRAARVVHIINAEMENYEPGVYTERVLES 573

  Fly   502 AKCLAIN-LRIYGPQVFIAAKILWKYSNSSAANENFE--SFSDMWKWLTNEISMIAKKILVSINT 563
            .|.|:.. :..:..||.:|.:.|     |::..:.||  .|.|..:.:.:.:..|.|.:|:....
Zfish   574 IKLLSETVMPRFAEQVEVAIEAL-----STSPPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTP 633

  Fly   564 TKGDRDADAEK----------CESSSDKL--------TKSGVPATEDGEMVEYSGLEGKNNGDLN 610
            .:.:.|:|.|:          .::..|:|        ..:.:|..|..::.|......:....|:
Zfish   634 EELEDDSDFEQEDYDARSRTSIQTEDDQLIAGQSARAIMAQLPQEEKAKIAEQVESFRQEKSKLD 698

  Fly   611 TYQSKWSEDLSDDNDILKRAKNMSAMAFLMYQFTKGNGSLRTTQDLFTQAEYFAEEANRLYKVLR 675
            ...:||.:   :.|||:..||.|..:...|..||:|.|.|:.:.|:...|:..||..:|:.|:.|
Zfish   699 AEVAKWDD---NGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNSSDVINAAKKIAEAGSRMDKLAR 760

  Fly   676 HFSYQVPASDNKKDLLNILDRVPTFVQALQF--TVKDHTVGKAATFV-----KVDHVIRETKNLM 733
            ..:.|.|.|..|:|||..|.|:..:...|..  .||..........:     ....:|:..||||
Zfish   761 AVADQCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELIVSGLDSATSLIQAAKNLM 825

  Fly   734 NVINKVVSKCFECATKYK 751
            |.:...|...:..:|||:
Zfish   826 NAVVLTVKASYVASTKYQ 843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Catr	NP_726389.4	Vinculin	38..755	CDD:460040	184/858 (21%)
ctnna2	XP_005160129.1	Vinculin	18..866	CDD:460040	186/863 (22%)