Protein Alignment: alpha-Catr and Ctnnal1

• Sequence 1: NP_726389.4
• Gene: alpha-Catr
• FlyBaseID: FBgn0029105
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: NP_061231.3
• Gene: Ctnnal1
• MGIID: 1859649
• Length: 731
• Species: Mus musculus
• Alignment Length: 783
• Identity: 218/784 (28%)
• Similarity: 379/784 (48%)
• Gaps: 118/784 (15%)

  Fly     7 STVNNQRFRVRDMDNEQIMSTFGNIGHLLNIAVERFITIGEIIAEENIDIKGDMYEAAKEARDAG 71
            :|:.|.:...:..|  :.:.....:|..:|:||.||:.:||.||.||.|:|.::..|..||:.||
Mouse    48 TTLINHKDNTKKSD--KTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAG 110

  Fly    72 KSIERLCDISPLSGMELRHHIEPLKDYGAIILAARSLLSSVTRILLLVDIIVVKKLLTAKKRASE 136
            ::|..|.|::..|.:|....:..|.|...::.|||.||||||::|||.|.:|:|:::|::.:...
Mouse   111 ETIASLTDVTKRSHLESDGQVTILTDKTGVVQAARLLLSSVTKVLLLADRVVIKQIVTSRNKILA 175

  Fly   137 SLEKLESVMNFTEFVRAFSVFGTEMIELAYLTGHHRNSFKEERRRAQMFSARQILEKSIAILLTS 201
            ::|:||.|.:|.|||:.||.||.||:|.|:|||..:|..|:|:::|:|..||.:|||...:|||:
Mouse   176 TMERLEKVNSFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKKARMAVARAVLEKGTMMLLTA 240

  Fly   202 SKNSLIHSDCVIVKENRDTVFCQIRRAMDLIHFVVKDSIFDTAKHMPFEKQASNPNYENESIYTT 266
            ||..|.|..|.....|::.||.::|.|::.:..:|.|.           :.:...:..:.||:|.
Mouse   241 SKTCLRHPSCESAHTNKEGVFDRMRVALEKVTEIVTDC-----------RLSGETDSSSVSIFTG 294

  Fly   267 IKRIVNLIKRYKYQMSYYEGSGEGNNNSDAYFSFLDDDLWKSEKNLPSAAGGGRMVNNTNFRKHL 331
            ||.:                                                  .||....|:::
Mouse   295 IKEL--------------------------------------------------KVNIEALRENV 309

  Fly   332 SSESLDLREELSLAFEKLFEKAHDFTDSPYISHNHRKNILSYCDNCKLEFDLYLNTIMKDQHEGG 396
            ..||   :|.||.|.|.:.|...|||||.|.||.||:.||......:.|....|:..|:.|....
Mouse   310 CFES---KENLSAALEAVLEHVEDFTDSAYTSHEHRERILELSSQARTELQQLLSVWMQTQSRKT 371

  Fly   397 GGAGGVGGVGGGQVKGRSDPELGMLS---SLEELCKQL---VVSVSSQIEDFNESLKICSKLVKS 455
            ..|.             .:.||.:|.   ||:||.::|   .:.:::.:..|:..    ..::|:
Mouse   372 KSAA-------------EELELTVLKISHSLDELRRELHCTAMQLAADLLKFHAD----HVVLKA 419

  Fly   456 FHVLATNYDIDNLNQRSSKFHDCCDHIFDICKLLQHIAPTERLQVQAKCLAINLRIYGPQVFIAA 520
            ..|.....:::.|.:.:.|..:..:.:.:.|:||:||:.||.|::.........::.|.|:..||
Mouse   420 LKVTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAA 484

  Fly   521 KILWKYSNSSAANENFESFSDMWKWLTNEISMIAKKILVSINTTKGDRDADAEKCE--------- 576
            :.|..:.:|..|.||.:.|.:.|:...::::.:.::|.......:|      |:|:
Mouse   485 ETLTLHPSSKIAKENLDVFCEAWESQMSDMATLLREISDVFEGRRG------ERCDHLSLPKPTK 543

  Fly   577 -SSSDKLTKSGVPATEDGEMVEYSGLE-GKNNGDLNTYQSKWSEDLSDDNDILKRAKNMSAMAFL 639
             |::.|..|...|.:|:...:...||: |..:.|.:....||.:   ::|:|::..:|||.||:.
Mouse   544 NSANLKSLKPDKPDSEEQAKIAKLGLKLGLLSSDADCEIEKWED---EENEIVRHGRNMSRMAYS 605

  Fly   640 MYQFTKGNGSLRTTQDLFTQAEYFAEEANRLYKVLRHFSYQVPASDNKKDLLNILDRVPTFVQAL 704
            :|.||:|.|.|:|:|||....|.||.|..:|...::.||.|:...|....||.|...:|...| |
Mouse   606 LYLFTRGEGPLKTSQDLIHFLEVFAAEGLKLTSSVQSFSKQLKDDDKLMLLLEINKLIPLCHQ-L 669

  Fly   705 QFTVKDHTVGKAATFVKVDHVIRETKNLMNVINKVVSKCFECATKYKLNLTGITGGLTSERSNEN 769
            |...|  |..::..|:|||..|.:.:::|.::.:::|.|::...|.:.|..|      |..:.:.
Mouse   670 QTITK--TSLQSKVFLKVDKCITKIRSMMTLVVQLLSLCYKLLKKMENNRWG------SATNKDT 726

  Fly   770 MAG 772
            |.|
Mouse   727 MDG 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Catr	NP_726389.4	Vinculin	52..755	CDD:279395	201/720 (28%)
Ctnnal1	NP_061231.3	Vinculin	91..674	CDD:279395	189/674 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C80384785
eggNOG	1	0.900				E1_KOG3681
Hieranoid	1	1.000
Homologene	1	1.000				H2815
Inparanoid	1	1.050	293	1.000	Inparanoid score	I2738
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0006446
OrthoInspector	1	1.000				T1082205
orthoMCL	1	0.900				OOG5_133957
Panther	1	1.100			LDO	PTHR46342
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R5795
TreeFam	1	0.960
	13	12.790