Protein Alignment alpha-Catr and Ctnna1

DIOPT Version :10

• Sequence 1: NP_726389.4
• Gene: alpha-Catr / 49713
• FlyBaseID: FBgn0029105
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: NP_001007146.1
• Gene: Ctnna1 / 307505
• RGDID: 1359485
• Length: 908
• Species: Rattus norvegicus
• Alignment Length: 946
• Identity: 197/946 - (20%)
• Similarity: 329/946 - (34%)
• Gaps: 293/946 - (30%)

  Fly    33 HLLNIAVER----FITIGEIIAEENIDIKGDMYEAAKEARDAG---KSIERLCDISPLSGMELRH 90
            |:|..:||:    |:..|:.||:|:..:|.::..|..:.|..|   ||........|.|.::
  Rat    59 HVLAASVEQATENFLEKGDKIAKESQFLKEELVAAVDDVRKQGDLMKSAAGEFADDPCSSVK--- 120

  Fly    91 HIEPLKDYGAIILAARSLLSSVTRILLLVDIIVVKKLLTAKKRASESLEKLESVMNFTEFVRAFS 155
                   .|.::.|||:|||:|||:|:|.|:..|.|||...|...:.:.||.:..|..:....:.
  Rat   121 -------RGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYR 178

  Fly   156 VFGTEMIELAYLTGHHRNSFKEERRRAQMFSARQILEKSIAILLTSSKNSLIHSDCVIVKENRDT 220
            ....|:.:|..:....:...|:...|.||.:||.||:|::.||.|:|:..|.|.|....|.|||.
  Rat   179 ALKPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDL 243

  Fly   221 VFCQIRRAMDLIHFVVKDSIFDTAKHMPFEKQASNPNYENESIYTTIKRIVNLIKRYKYQMSYYE 285
            ::.|:::|:..|....:.:..|.|                                     |..:
  Rat   244 IYKQLQQAVTGISNAAQATASDDA-------------------------------------SQQQ 271

  Fly   286 GSGEGNNNSDAYFSFLDDDLWKSEKNLPSAAGGGRMVNN-TNFRKHLSSESLDLREE-----LSL 344
            |.|                           .|||.:... .||.|.:..:.|...||     |..
  Rat   272 GGG---------------------------GGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEE 309

  Fly   345 AFEKLFEKAHDFTDSPYISHNHRKNILSYCDNCKLEFDLYLNTIMKDQHEGGGGAGGVGGVGGGQ 409
            ..|.:...|....||.....:.|:.|::.|:..:......|:..|       |.||.
  Rat   310 RLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYM-------GNAGR-------- 359

  Fly   410 VKGRSDPELGMLSSLEELCK-------QLVVSVSSQIED-FNESLKICSKLVKSFHVLATNYDID 466
             |.|||   .:.|:::::.|       ||..:|...:.| |.|:......|:::    |.|.:..
  Rat   360 -KERSD---ALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEA----AKNGNEK 416

  Fly   467 NLNQRSSKFHDCCDHIFDICKLLQHIAPTERLQVQAKCLAINLRIYGPQVFIAAKILWKYSNSSA 531
            .:.:.:..|.:..:.:.::..|...|:..|......:..|..|....|||..||..|.....|..
  Rat   417 EVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKL 481

  Fly   532 ANENFESFSDMW----KWLT---NEISMIAKKILVSINTTKGD----------RDAD-------- 571
            |.||.:.|.:.|    :.||   ::|:.|...:.||.|....|          :|.|
  Rat   482 AQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGA 546

  Fly   572 -------------------------------------------AEKCESSSDKLTKSGVPATEDG 593
                                                       .|:.|::.:.|:.......::.
  Rat   547 IRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDEN 611

  Fly   594 EMVE-----YSGL-------------EGKNNGDLNT----YQSKWSEDLSDD------------- 623
            |.::     |.|:             |..::.|..|    .:|:.|....||
  Rat   612 EFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTEDDQLIAGQSARAIMA 676

  Fly   624 -----------------------------------NDILKRAKNMSAMAFLMYQFTKGNGSLRTT 653
                                               |||:..||.|..:...|..||:|.|.|:.|
  Rat   677 QLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNT 741

  Fly   654 QDLFTQAEYFAEEANRLYKVLRHFSYQVPASDNKKDLLNILDRVPTFVQALQFTVK----DHTVG 714
            .|:.:.|:..||..:|:.|:.|..:...|.|..|:|||..|.|:..:...|....|    ...:|
  Rat   742 SDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLG 806

  Fly   715 KAATFVKVD---HVIRETKNLMNVINKVVSKCFECATKYK-------LNLTGITGGLTSERSNEN 769
            .......||   .:|:..|||||.:.:.|...:..:|||:       |||..::..:.:
  Rat   807 GELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVASTKYQKSQGMASLNLPAVSWKMKA------ 865

  Fly   770 MAGGMCDSKGTTSSSDIPXHYGMARRAKGDARRTRV 805
                             | ...:.:|.|.|..:|::
  Rat   866 -----------------PEKKPLVKREKQDETQTKI 884

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Catr	NP_726389.4	Vinculin	38..755	CDD:460040	189/889 (21%)
Ctnna1	NP_001007146.1	Vinculin	19..869	CDD:460040	193/929 (21%)