Protein Alignment alpha-Catr and Vcl

DIOPT Version :9

• Sequence 1: NP_726389.4
• Gene: alpha-Catr / 49713
• FlyBaseID: FBgn0029105
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: XP_038949159.1
• Gene: Vcl / 305679
• RGDID: 1311217
• Length: 1135
• Species: Rattus norvegicus
• Alignment Length: 1149
• Identity: 169/1149 - (14%)
• Similarity: 315/1149 - (27%)
• Gaps: 502/1149 - (43%)

  Fly    38 AVERFITIGEIIAEENID--IKGDMYEAAKEARDAGKSIERLCDISPLSGMELRHHIEPLKDYGA 100
            ||...:.:|:...:...|  :|.||..|..:..:|...:.:...:     ::...:..|.:||
  Rat    50 AVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQM-----LQSDPYSVPARDY-- 107

  Fly   101 IILAARSLLSSVTRILLLVDIIVVKKLLTAKKRASESLEKLESVMNFTEFVRAFSVFGTEMIELA 165
            :|..:|.:||..:.:||..|...|:|::...|...|.|...|.|....:.|......|..|.::|
  Rat   108 LIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMA 172

  Fly   166 YLTGHHRNSFKEERRRAQMFSARQILEKSIAILLTSSKNSLIHSDCVIVKENRDTVFCQIRRAMD 230
            .:....:.....:..|..:.::...:::.:.:|:::.|
  Rat   173 KMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK--------------------------- 210

  Fly   231 LIHFVVKDSIFDTAKHMPFEKQASNPNYENESIYTTIKRIVNLIKRYKYQMSYYEGSGEGNNNSD 295
             |....|:|     |:...|:...|.|:....:...|..|:.:::...:
  Rat   211 -IFVTTKNS-----KNQGIEEALKNRNFTVGKMSAEINEIIRVLQLTSW---------------- 253

  Fly   296 AYFSFLDDDLWKSEKNL-----------------------PSAAGG-----------------GR 320
                  |:|.|.|:|:.                       |:|:.|                 |.
  Rat   254 ------DEDAWASKKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGE 312

  Fly   321 MVNNTNFRK---------HLSSESLDLR---------------------EELSLAFEKLFEKAHD 355
            :......|:         .::.:..|||                     :.|:...|....|...
  Rat   313 LCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEA 377

  Fly   356 FTDSPY-------ISHN--------------------HRKNILSYCDNCKLEFDLY--------L 385
            .|:|..       .:.|                    ..:.|...||:.|...|:.        |
  Rat   378 MTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEIAAL 442

  Fly   386 NTIMKDQHEGGGG---------------------------------------AGGV--------- 402
            .:.:.|....|.|                                       .|.:
  Rat   443 TSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDN 507

  Fly   403 -----GGVGGGQVKG----------------RSDPELGMLSSLEELCKQL-------------VV 433
                 .|||...::|                |.| .|.....:::|..||             ..
  Rat   508 PTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQD-LLAKCDRVDQLAAQLADLAARGEGESPQAR 571

  Fly   434 SVSSQIEDFNESLKI----------------CSKLVKSFHVLAT-NYDIDN----LNQRSSKFHD 477
            :::||::|..:.||.                .:..:|...|.|| ..|..|    .::|::.|.:
  Rat   572 ALASQLQDSLKDLKTQMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFEN 636

  Fly   478 CCDHIFDICKLLQHI-----APTERLQVQAKCLAINLRIYGPQVFIAAKILWKYSNSSAANENFE 537
            ....:....:....:     :..|.:|...|    ..|...|||..||:||.:...:.||.|:||
  Rat   637 HSGRLGATAEKAAAVGAANKSTVEGIQASVK----TARELTPQVISAARILLRNPGNQAAYEHFE 697

  Fly   538 SFSDMW--------------------------------------------KWLTNEISMIAKK-- 556
            :..:.|                                            :.|....:.||::
  Rat   698 TMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRAN 762

  Fly   557 --ILVSINTTKGDRDAD-AEKCESSSDKLTK---------------------------SGV---- 587
              :||:....:...|.. .|..:::||:|:|                           ||.
  Rat   763 RILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILG 827

  Fly   588 ---------------------------------------------------PATEDGEMVEYSGL 601
                                                               |..:|.|..|....
  Rat   828 AVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAG 892

  Fly   602 EGKNN------GDLNTYQSKWS-----------------------------EDLSDD-------- 623
            |..|.      ..|:....|||                             .|:.||
  Rat   893 EVINQPMMMAARQLHDEARKWSSKPGLPAAQVGIGVVAEADAADAVGFPFPSDMEDDSEPELLLV 957

  Fly   624 ----------------------------NDILKRAKNMSAMAFLMYQFTKGNGSLRTTQDLFTQA 660
                                        |||:..||.|:.:...|.:..:|...  |.:.|...|
  Rat   958 PANQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSG--TKRALIQCA 1020

  Fly   661 EYFAEEANRLYKVLRHFSYQVPASDNKKDLLNILDRVPTFVQALQF--TVKDHTVGKA------- 716
            :..|:.::.:.::.:..:.|......:.:||.:.:|:||....|:.  |||...:|:.
  Rat  1021 KDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEES 1085

  Fly   717 --ATFVKVDHVIRETKNLMNVINKVVSKCFECATKYKLNLTGIT 758
              ||    :.::...:|||..:.:.|.:....:.|.:.: .|.|
  Rat  1086 EQAT----EMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFT 1124

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Catr	NP_726389.4	Vinculin	52..755	CDD:279395	164/1130 (15%)
Vcl	XP_038949159.1	Vinculin	66..1135	CDD:395830	166/1133 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3681
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810