Protein Alignment alpha-Catr and Ctnna3

DIOPT Version :10

• Sequence 1: NP_726389.4
• Gene: alpha-Catr / 49713
• FlyBaseID: FBgn0029105
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: NP_808280.2
• Gene: Ctnna3 / 216033
• MGIID: 2661445
• Length: 895
• Species: Mus musculus
• Alignment Length: 843
• Identity: 181/843 - (21%)
• Similarity: 318/843 - (37%)
• Gaps: 223/843 - (26%)

  Fly    46 GEIIAEENIDIKGDMYEAAKEARDAGK----SIERLCDISPLSGMELRHHIEP--LKDYGAIILA 104
            ||:||:|...:|.::..|.:|.|...|    |.||..|             :|  |....|::.|
Mouse    73 GEMIAKEATVLKEELAAALQEVRKESKALKVSAERFTD-------------DPCYLPKREAVVQA 124

  Fly   105 ARSLLSSVTRILLLVDIIVVKKLLTAKKRASESLEKLESVMNFTEFVRAFSVFGTEMIELAYLTG 169
            ||:||::|||:|:|.|:|.|..||........:.|.|::|.|.::..|.:...|.|:..|.||..
Mouse   125 ARALLAAVTRLLVLADMIDVMCLLQHVSSFQRTFESLKNVSNKSDLQRTYQKLGKELESLDYLAF 189

  Fly   170 HHRNSFKEERRRAQMFSARQILEKSIAILLTSSKNSLIHSDCVIVKENRDTVFCQIRRAMDLIHF 234
            ..:...|...:|.::..||..|:::..:|.:.....|.|||...:|.::|||..:|:.|:|:|
Mouse   190 KRQQDLKSPSQRDEIAGARATLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALDVI-- 252

  Fly   235 VVKDSIFDTAKHMPFEKQASNPNYENESIYTTIKRIVNLIKRYKYQMSYYEGSGEGNNNSDAYFS 299
                    :......:...:.|..:..::.:....:.|||......::
Mouse   253 --------SNASQGIQNAPAPPEPQAATLGSAFDELENLIVLNPLTVT----------------- 292

  Fly   300 FLDDDLWKS-EKNLPSAAGGGRMVNNTNFRKHLSSESL------------DLREE---------- 341
              ::|:..| ||.|.:...|..::.:::..:.|..|.:            ||..|
Mouse   293 --EEDVRPSLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLTEYMSNTGKTER 355

  Fly   342 ---LSLAFEKLFEKAHDFTDSPYISHNHRKNILSYCDNCKLEFDLYLNTI-----------MKDQ 392
               |:.|...:.:|..|      :....||.|:.:..:..|:..:.|..:           :||.
Mouse   356 SNTLNTAIVNMSKKTRD------LRRQLRKAIIDHISDSFLDTTVPLLVLIEAAKNGRVKEIKDY 414

  Fly   393 ----HEGGGGAGGVGGVGGGQVKGRSDPELGMLSS--LEELCKQLVVSVSSQIEDFNESLKICSK 451
                ||..|....|..:...........::..:::  ||.||.|::          |.:|.:.|:
Mouse   415 AAIFHEHTGRLVEVANLACSMSTNEDGIKIVRIAANHLETLCPQII----------NAALALASR 469

  Fly   452 ----LVKS------------FHVLATNYDIDNLNQRSSKFHDCCDHIFDICKLLQHIAPTER--L 498
                :||:            .|||....|                   ||..:...:|.:|.  |
Mouse   470 PKSQVVKNTMEMYKRTWEHYIHVLTEAVD-------------------DITSIDDFLAVSESHIL 515

  Fly   499 QVQAKCL-------AINL-RIYGPQVFIAAKIL------------WKYSNSSAANENFESFSDMW 543
            :...||:       |.|| |..|.....||::.            ..|:.....|.||.:.:.:.
Mouse   516 EDVNKCIIALRDQDADNLDRAAGAIRGRAARVAHIVAGEMDSYEPGAYTEGVMRNVNFLTSTVIP 580

  Fly   544 KWLT-------------------NEISMIAKKILVSINTTK---------------GDRDADAE- 573
            :::|                   |:...|:|||..:|:..:               .|.:.|.|
Mouse   581 EFVTQVNVALDALSKNSLTALDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEDDHEV 645

  Fly   574 ------KCESSSDKLTKSGVPATEDGEMVEYSGLEGKNNGDLNTYQSKWSEDLS--DD--NDILK 628
                  :.|..:|:...:.:|..|..::.|       ...|....:||...::.  ||  |||:.
Mouse   646 RSHTSIQTEGKTDRAKMTQLPEAEKEKIAE-------QVADFKKVKSKLDAEIEIWDDTSNDIIV 703

  Fly   629 RAKNMSAMAFLMYQFTKGNGSLRTTQDLFTQAEYFAEEANRLYKVLRHFSYQVPASDNKKDLLNI 693
            .||.|..:...|..||:|.|.|:.|.|:...|:..:|..:|:..:.|..:.|.|....|:|||..
Mouse   704 LAKKMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPPCKQDLLAY 768

  Fly   694 LDRVPTFVQAL----QFTVKDHTVGKAATFVKVDHV---IRETKNLMNVINKVVSKCFECATK 749
            |:::..:...|    |...:...:|.......:|.|   |:..|||||.:.:.|...:..:||
Mouse   769 LEQIKFYSHQLKICSQVKAEIQNLGGELIVSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTK 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Catr	NP_726389.4	Vinculin	38..755	CDD:460040	181/843 (21%)
Ctnna3	NP_808280.2	Vinculin	18..856	CDD:460040	181/843 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	635..660		5/24 (21%)