Protein Alignment alpha-Catr and ctn-1

DIOPT Version :10

• Sequence 1: NP_726389.4
• Gene: alpha-Catr / 49713
• FlyBaseID: FBgn0029105
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: NP_001364770.1
• Gene: ctn-1 / 171818
• WormBaseID: WBGene00000832
• Length: 812
• Species: Caenorhabditis elegans
• Alignment Length: 809
• Identity: 276/809 - (34%)
• Similarity: 409/809 - (50%)
• Gaps: 128/809 - (15%)

  Fly    21 NEQIMSTFGNIGHLLNIAVERFITIGEIIAEENIDIKGDMYEAAKEARDAGKSIERL---CDISP 82
            :|:.|.....||..:..|:|||:.:||.||:||.||:.:||:|..|||.||.|:..|   |:..|
 Worm    83 SERAMRAALKIGSAVEAAIERFVCVGETIADENADIQPEMYDACTEARLAGASMANLSCACNDDP 147

  Fly    83 LSGMELRHHIEPLKDYGAIILAARSLLSSVTRILLLVDIIVVKKLLTAKKRASESLEKLESVMNF 147
            .|          :.|...::.|:|.|||||||:|||.|.::||::|.|:.:.:.||.:|||..:|
 Worm   148 NS----------VVDKAVLVRASRQLLSSVTRVLLLADRVLVKQVLRAEDKIAFSLSRLESTRSF 202

  Fly   148 TEFVRAFSVFGTEMIELAYLTGHHRNSFKEERRRAQMFSARQILEKSIAILLTSSKNSLIHSDCV 212
            .:||:.|:|||.||:|||:.:|..::..|.|:|:|||..||..||:...:|||:||..|.|.||.
 Worm   203 NDFVKVFAVFGGEMVELAHRSGDRQHDLKSEKRKAQMSIARTSLERLTMLLLTASKTYLRHPDCD 267

  Fly   213 IVKENRDTVFCQIRRAMDLIHFVVKDSIFDTAKHMPFEKQASNP---------NYENESIYTTIK 268
            ...:.||.||.|::.:::||...|.|.|..|.|....:.:...|         |       ..||
 Worm   268 SALQCRDGVFYQMKLSLELIAICVCDGILTTEKSRYIQDEPDMPIDIALQLTAN-------AAIK 325

  Fly   269 RIVNLIKRYKYQMSYYEGSGEGNNNSDAYFSFLDDDLWKSEKNLPSAAGGGRMVNNTNFRKHLSS 333
            ::..:::..:  |:...|:|
 Worm   326 QLTEMLEMIR--MTVRVGAG--------------------------------------------- 343

  Fly   334 ESLDLREELSLAFEKLFEKAHDFTDSPYISHNHRKNILSYCDNCKLEFDLYLNTIMKDQHEGGGG 398
                :||.:..|.:.|.:...|||||.|..|:.|:.||.:.:.|:.|.   .|.|..|::|....
 Worm   344 ----VRERIVSALDALCQLTQDFTDSAYTPHHQREQILDFLEECRFEM---TNLIQPDENEQLAA 401

  Fly   399 AGGVGGVGGGQVKGRSDPELGMLS-SLEELCKQLVVSVSSQIEDF---NESLKICSKLVKSFHVL 459
            :|             .:..:..|: .|::|.|||.:....||.:.   ||.    ..|:.|....
 Worm   402 SG-------------LEVTVERLNRRLKDLSKQLQIVAMEQISEVLRANED----QVLLSSMKAC 449

  Fly   460 ATNYDIDNLNQRSSKFHDCCDHIFDICKLLQHIAPTERLQVQAKCLAINLRIYGPQVFIAAKILW 524
            |.:.|||.:.:...||.:..||:.::|:||.||:.|:.|.|....:..|:|...|...:|.:.|.
 Worm   450 AVSGDIDGVEKYMHKFREHADHMQEVCRLLHHISITDALHVHTGHVERNMRALAPLTILAGRTLC 514

  Fly   525 KYSNSSAANENFESFSDMWKWLTNEISMIAKKILVSINTTKGDRDADAEKCESSSDKLTKSGV-- 587
            .:.:|..|.||.|.|.|.|....|::|.:||:..|:.|    .|.|..::...|..:..|.|.
 Worm   515 VHPSSRIARENLEVFCDTWGQAVNDLSRVAKESDVAAN----GRVAAEKQAYMSLPRPGKHGTTQ 575

  Fly   588 ----PAT---EDGEMVEYSGLEGK-NNGDLNTYQSKWSEDLSDDNDILKRAKNMSAMAFLMYQFT 644
                |.|   ||.:.:...|||.| ...:::....||.|  ..:|||:||||.||:||:.||.||
 Worm   576 KPSKPITLDVEDQQKMAKVGLEMKLLTSEVDAEAEKWDE--YAENDIVKRAKAMSSMAYNMYLFT 638

  Fly   645 KGNGSLRTTQDLFTQAEYFAEEANRLYKVLRHFSYQVPASDNKKDLLNILDRVPTFVQALQFTVK 709
            :|:|.|:||.|||||||:|||:||::|:.:|.|||:||.|..|.||..||:|:|...|.||..||
 Worm   639 RGDGPLKTTHDLFTQAEFFAEQANQMYRTVREFSYEVPGSAEKSDLSAILERIPLHCQQLQVMVK 703

  Fly   710 DHTVGKAATFVKVDHVIRETKNLMNVINKVVSKCFECATK-YKLNLTGITGGLTSERSNENMAGG 773
            ..||||.|||.|||.||:|||||||.|.|:|:..|.|||| ::.:..|:........|   |.|.
 Worm   704 SPTVGKTATFGKVDSVIQETKNLMNEIAKLVTASFVCATKMFQDSQQGMKSSFAEVLS---MGGR 765

  Fly   774 MCDSKGTTSSSDIPXHYGMARRAKGDARR 802
            :...||..::    ..:|...:|..:.||
 Worm   766 VPTVKGQVAN----RLFGAGHQASDEPRR 790

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Catr	NP_726389.4	Vinculin	38..755	CDD:460040	262/743 (35%)
ctn-1	NP_001364770.1	Vinculin	48..751	CDD:460040	266/761 (35%)