Protein Alignment alpha-Catr and Ctnna2

DIOPT Version :10

• Sequence 1: NP_726389.4
• Gene: alpha-Catr / 49713
• FlyBaseID: FBgn0029105
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: NP_033949.2
• Gene: Ctnna2 / 12386
• MGIID: 88275
• Length: 953
• Species: Mus musculus
• Alignment Length: 917
• Identity: 194/917 - (21%)
• Similarity: 352/917 - (38%)
• Gaps: 256/917 - (27%)

  Fly    33 HLLNIAVER----FITIGEIIAEENIDIKGDMYEAAKEARDAGKSI----ERLCDISPLSGMELR 89
            |:|..:||:    |:..||.||:|:.|:|.::..|.::.|..|:::    ....| .|.|.::
Mouse    58 HVLAASVEQATQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSEFAD-DPCSSVK-- 119

  Fly    90 HHIEPLKDYGAIILAARSLLSSVTRILLLVDIIVVKKLLTAKKRASESLEKLESVMNFTEFVRAF 154
                    .|.::.|||:|||:|||:|:|.|:..|.:||:..|...|:||.:::..|..:....|
Mouse   120 --------RGTMVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRF 176

  Fly   155 SVFGTEMIELAYLTGHHRNSFKEERRRAQMFSARQILEKSIAILLTSSKNSLIHSDCVIVKENRD 219
            ..||.||::|.|:....:...|:...|.:|.:||..|:|:..:|.|:|:..|.|.|....:.|||
Mouse   177 KEFGKEMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRD 241

  Fly   220 TVFCQIRRAMDLIHFVVKDSIFDTAKHMPFEKQASNPNYENESIYTTIKRIVNLIKRYKYQ---- 280
            .||.|::.|:..|....               ||::|..|.:. :|.|..:...:..:..:
Mouse   242 YVFKQVQEAIAGISSAA---------------QATSPTDEAKG-HTGIGELAAALNEFDNKIILD 290

  Fly   281 -MSYYEGSGEGNNNSDAYFSFLDDDLWKSEKNLPSAAGGGRMVNNTNF-----RKHLSSESLDLR 339
             |::          |:|.|.      ...|:.|.|...|..::.:::.     |:.:.:|...:|
Mouse   291 PMTF----------SEARFR------PSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVR 339

  Fly   340 --------------------EELSLAFEKLFEKAHDFTDSPYISHNHRKNILSYCDNCKLEFDLY 384
                                :.|::|.:|:.:|..|      :....||.::.:..:..||.::.
Mouse   340 QALQDLLSEYMNNTGRKEKGDPLNIAIDKMTKKTRD------LRRQLRKAVMDHISDSFLETNVP 398

  Fly   385 LNTIMKDQHEGGGGAGGVGGVGGGQVK---------------------GRSDPELGM------LS 422
            |..:::....|          ...:||                     ..|:.|.|:      .:
Mouse   399 LLVLIEAAKSG----------NEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKLVRMAAT 453

  Fly   423 SLEELCKQLV------------------------------------VSVSSQIEDF-----NESL 446
            .::.||.|::                                    |...:.::||     |..|
Mouse   454 QIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHIL 518

  Fly   447 KICSKLVKSFHVLATNYDIDNLNQRSSKFHD--------------------CCDHIFDICKLL-Q 490
            :..:|.|    :.....|:|.|::.:.....                    ..:.:.:..||| :
Mouse   519 EDVNKCV----IALQEGDVDTLDRTAGAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSE 579

  Fly   491 HIAP--TERLQVQAKCLAINLRIYGPQVFIAAKILWKYSNSSAANENFESFSDMWKWLTNEISMI 553
            .:.|  .|:::|..:.|:.|:    ||.|               .||  .|.|..:.:.:.:..|
Mouse   580 TVMPRFAEQVEVAIEALSANV----PQPF---------------EEN--EFIDASRLVYDGVRDI 623

  Fly   554 AKKILVSINTTKGDRDADAEK----------CESSSDKL--------TKSGVPATEDGEMVEYSG 600
            .|.:|:.....:.:.|:|.|:          .::..|:|        ..:.:|..|..::.|...
Mouse   624 RKAVLMIRTPEELEDDSDFEQEDYDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEEKAKIAEQVE 688

  Fly   601 LEGKNNGDLNTYQSKWSEDLSDDNDILKRAKNMSAMAFLMYQFTKGNGSLRTTQDLFTQAEYFAE 665
            :..:....|:...:||.:   ..|||:..||.|..:...|..||:|.|.|:.|.|:...|:..||
Mouse   689 IFHQEKSKLDAEVAKWDD---SGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVINAAKKIAE 750

  Fly   666 EANRLYKVLRHFSYQVPASDNKKDLLNILDRVPTFVQALQFTVKDHTVGKAATFVKVDHVIRETK 730
            ..:|:.|:.|..:.|.|.|..|:|||..|.|:..:...|....|               |..|.:
Mouse   751 AGSRMDKLARAVADQCPDSACKQDLLAYLQRIALYCHQLNICSK---------------VKAEVQ 800

  Fly   731 NL---MNVINKVVSKCFECATKYKLNLTGITGGLTSERSNE--NMAGGMCDSKGTTSSSDIPXHY 790
            ||   :.|....|...|  .|.|:::...|.||..|:.|..  ..|.|.....|::.||.:....
Mouse   801 NLGGELIVSGTGVQSTF--TTFYEVDCDVIDGGRASQLSTHLPTCAEGAPIGSGSSDSSMLDSAT 863

  Fly   791 GMARRAK 797
            .:.:.||
Mouse   864 SLIQAAK 870

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Catr	NP_726389.4	Vinculin	38..755	CDD:460040	180/866 (21%)
Ctnna2	NP_033949.2	Vinculin	18..914	CDD:460040	194/917 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	912..939