Protein Alignment alpha-Catr and ctnnal1

DIOPT Version :10

• Sequence 1: NP_726389.4
• Gene: alpha-Catr / 49713
• FlyBaseID: FBgn0029105
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: NP_001137526.1
• Gene: ctnnal1 / 100034581
• ZFINID: ZDB-GENE-060503-507
• Length: 754
• Species: Danio rerio
• Alignment Length: 764
• Identity: 209/764 - (27%)
• Similarity: 363/764 - (47%)
• Gaps: 123/764 - (16%)

  Fly     7 STVNNQRFRVRDMDNEQIMSTFGNIGHLLNIAVERFITIGEIIAEENIDIKGDMYEAAKEARDAG 71
            :|:.|.:.:::  ..|:.:.....:|..:::||.||:.:||.||.||.|:|.:|..|..|||.||
Zfish    34 TTLINHKDKLK--KTEKTLRAIQRVGQAVSVAVGRFVAVGEAIAAENEDLKEEMGLACFEARRAG 96

  Fly    72 KSIERLCDISPLSGMELRHHIEPLKDYGAIILAARSLLSSVTRILLLVDIIVVKKLLTAKKRASE 136
            ..|.:|.|:|.|...:.........|...::.|||.||||||::|:|.|.||:|::::::.:...
Zfish    97 TGIAQLTDVSSLEHCDGDGRSTVFSDRTGMVKAARMLLSSVTKVLVLADCIVIKQIISSRNKVLV 161

  Fly   137 SLEKLESVMNFTEFVRAFSVFGTEMIELAYLTGHHRNSFKEERRRAQMFSARQILEKSIAILLTS 201
            :||:||.|..|.|||:.||.||.||:|.|:|||..:|..|:|::||:|.:||.:|||...:|||:
Zfish   162 TLEQLERVSTFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKRARMAAARAVLEKCTMMLLTA 226

  Fly   202 SKNSLIHSDCVIVKENRDTVFCQIRRAMDLIHFVVKDS-IFDTAKHMPFEKQASNPNYENESIYT 265
            ||..|.|.||...:.|::.||.::|.|::.:..:|.|: ....||.:|.            |||.
Zfish   227 SKTCLRHPDCESARINKEAVFQRMRIALEQVIEIVTDTRSSGEAKALPV------------SIYA 279

  Fly   266 TIKRI---VNLIKRYKYQMSYYEGSGEGNNNSDAYFSFLDDDLWKSEKNLPSAAGGGRMVNNTNF 327
            .||..   |..::...|.:|.
Zfish   280 GIKDFKVKVEALRDSLYGVSC-------------------------------------------- 300

  Fly   328 RKHLSSESLDLREELSLAFEKLFEKAHDFTDSPYISHNHRKNILSYCDNCKLEFDLYLNTIMKDQ 392
                        |.::...|.|.||..|||||.|..|..|:.|:..|...:.|....:||....|
Zfish   301 ------------EAVAAQLEALVEKTEDFTDSAYTRHEQRETIIQLCQITRQETKQLINTWRHAQ 353

  Fly   393 HEGGGGAGGVGGVGGGQVKGR---SDPELGML------SSLEELCKQLVVSVSSQIEDFNESLKI 448
                            .:|.:   .:.||.:|      |.|.:...::.|..::::      ||:
Zfish   354 ----------------SLKAKEATDEMELSILKTCQCVSDLRQELHKVAVGRATEL------LKL 396

  Fly   449 CSK--LVKSFHVLATNYDIDNLNQRSSKFHDCCDHIFDICKLLQHIAPTERLQVQAKCLAINLRI 511
            .|.  ::::......:.:::.:...:|...:..:.:.:.|:||.|::.||.|::.........|:
Zfish   397 HSDHLVLQALKASGGDGNLEAVADYASTLTEHNEQLVETCRLLCHVSGTEPLEITCIHAEETFRV 461

  Fly   512 YGPQVFIAAKILWKYSNSSAANENFESFSDMWKWLTNEISMIAKKILVSINTTKGDR----DADA 572
            .|||:..||:.|..:..|..|.||.:.|.:.|:....:::::.|:|.......:||:    ....
Zfish   462 IGPQIISAAQTLALHPTSKIAKENLDVFCEAWESQLCDMAILLKEINDVFEGRRGDKKTYLSLPR 526

  Fly   573 EKCESSSDKLTKSGVPATEDGEMVEYSGLE-GKNNGDLNTYQSKWSEDLSDDNDILKRAKNMSAM 636
            ....|::.|..|:.....|:...:...||| .....|:::...:|.|   .|:::::..:.:|:|
Zfish   527 PGKHSANLKTVKAAKLDAEEQTTIAKLGLELCLLTSDVDSEVERWDE---QDHEMVRLCQIISSM 588

  Fly   637 AFLMYQFTKGNGSLRTTQDLFTQAEYFAEEANRLYKVLRHFSYQVPASDNKKDLLNILDRVPTFV 701
            |:.||.||:|.|.|:||.|||.|||..:::..:|..||:..|.|: ..:::..:::..:::.:..
Zfish   589 AYSMYLFTRGEGLLKTTSDLFHQAEVLSDQGLQLCPVLQSLSTQL-LDEDRMLIISETEKLSSAC 652

  Fly   702 QALQFTVKDHTVGKAATFVKVDHVIRETKN-------LMNVINKVVSKC 743
            |.||...|....||:|.|.|||..|:.||.       |:.:.||::.||
Zfish   653 QQLQACAKTPVQGKSAIFQKVDSSIQNTKGILILVVYLLPICNKLIRKC 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Catr	NP_726389.4	Vinculin	38..755	CDD:460040	205/733 (28%)
ctnnal1	NP_001137526.1	Vinculin	16..>510	CDD:460040	154/567 (27%)