Protein Alignment l(2)37Bb and M04B2.4

DIOPT Version :10

• Sequence 1: NP_536791.1
• Gene: l(2)37Bb / 49427
• FlyBaseID: FBgn0002021
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_502171.1
• Gene: M04B2.4 / 178073
• WormBaseID: WBGene00010847
• Length: 527
• Species: Caenorhabditis elegans
• Alignment Length: 499
• Identity: 170/499 - (34%)
• Similarity: 263/499 - (52%)
• Gaps: 39/499 - (7%)

  Fly    34 GEDLHPIRRTLRLLGNDMRKVKEFFVPKEPETEKVPIPTQSQFHFSGERDKSKEATVPDDFQTHC 98
            |||:  ::|....|..|.|:.|..|.....:..|...|.....|  |..|.       :.|....
 Worm    41 GEDV--MKRVWHGLSYDFRRWKRRFQEARKDAFKRRHPIAHMKH--GTLDN-------EVFPYRA 94

  Fly    99 DVLIIGGGGVGSSIAYWLKEKARD-GLNVVVVEKDDTYAQSATRVSVGGLCQQFSLPENIQMSLF 162
            :::|||||..|||.|:||||:.|| ...|||||.:|.:.:|:|.:|.||:.||||:||.:.||||
 Worm    95 EIVIIGGGLSGSSTAFWLKERFRDEDFKVVVVENNDVFTKSSTMLSTGGITQQFSIPEFVDMSLF 159

  Fly   163 AADFLRSARKHF----GEEVPLQFTPHGHLMLA-GEEHAESLKRSSQLQNELGARNELLTADRLT 222
            ..:|||.|.:|.    .|:..:.|.|.|:|.|| .:|..|.::.:.::|.|.||:.:||:.|.||
 Worm   160 TTEFLRHAGEHLRILDSEQPDINFFPTGYLRLAKTDEEVEMMRSAWKVQIERGAKVQLLSKDELT 224

  Fly   223 ARFPWLNTKGIALGCLGLEKEGWFNPLALLSNFRRSASGYGAHFISGQVVDFEFKSQTDISVVTD 287
            .|:|::|...:.|..||:|.||..:...|||..|......|..::.|:|..|:|:.....|.|..
 Worm   225 KRYPYMNVDDVLLASLGVENEGTIDTWQLLSAIREKNITLGVQYVKGEVEGFQFERHRASSEVHA 289

  Fly   288 LGSNEGAYTGLEKA-----VI---QLPDGTRRTCKFALCVISAGASSEQIARLARIGVGPGILRV 344
            .|.:..|.....:|     |:   |:.|.:.|..:..|.|.:||..:.|:|::|.||.|.|:|.|
 Worm   290 FGDDATADENKLRAQRISGVLVRPQMNDASARPIRAHLIVNAAGPWAGQVAKMAGIGKGTGLLAV 354

  Fly   345 PLPINARKRYMYAINSQAQSAPGM--NMPMTIDPS-GIFIRRDGLGGNYIC------VQDSTEEY 400
            |:||..|||.::.|     .||.:  ::|..|||| |:|.|:...|..::.      .:|:..::
 Worm   355 PVPIQPRKRDVFVI-----FAPDVPSDLPFIIDPSTGVFCRQTDSGQTFLVGRTPSKEEDAKRDH 414

  Fly   401 NSAMIDPQYFAQHIRPHLYNRIPVLGEAQVVDSWAGCYDHNVYDENGILGAHPYYNNLYLATGFS 465
            ::..:|...|.|.|.|.|.:|:|....|:|..:|:|..|.|.:|:..::|.||.|.||::..||.
 Worm   415 SNLDVDYDDFYQKIWPVLVDRVPGFQTAKVKSAWSGYQDINTFDDAPVIGEHPLYTNLHMMCGFG 479

  Fly   466 GHGVQQSLAVGRAISELIMDGQFRTIDLSRLSFDRLIVDQPMFE 509
            ..||..|:|..||.:|.|.||.:..::|.:....|::...|:.|
 Worm   480 ERGVMHSMAAARAYAERIFDGAYINVNLRKFDMRRIVKMDPITE 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Bb	NP_536791.1	DadA	113..500	CDD:440429	144/409 (35%)
M04B2.4	NP_502171.1	DadA	93..514	CDD:440429	152/425 (36%)