Protein Alignment SERCA and ACA2

DIOPT Version :10

• Sequence 1: NP_726381.1
• Gene: SERCA / 49297
• FlyBaseID: FBgn0263006
• Length: 1020
• Species: Drosophila melanogaster
• Sequence 2: NP_195479.1
• Gene: ACA2 / 829918
• AraportID: AT4G37640
• Length: 1014
• Species: Arabidopsis thaliana
• Alignment Length: 1043
• Identity: 292/1043 - (27%)
• Similarity: 471/1043 - (45%)
• Gaps: 204/1043 - (19%)

  Fly    11 QSLNFFG----------TDPERGLTLD--QIKANQKKYGPNELPTEEGKSIWQLVLEQFDDLLVK 63
            :.|.|.|          ..|..||:.:  |:...|:.:|.|:....|.:..|..|.|...|:.:.
plant   111 KKLKFHGGVDGLAGKLKASPTDGLSTEAAQLSQRQELFGINKFAESEMRGFWVFVWEALQDMTLM 175

  Fly    64 ILLLAAIISFVLALFEE------HEETFTAFVEPLVILLILIANAVVGVWQERNAESAIEALKEY 122
            ||.:.|.:|.::.:..|      |:....|    ..|||::...|.....|...       .::.
plant   176 ILGVCAFVSLIVGIATEGWPKGSHDGLGIA----ASILLVVFVTATSDYRQSLQ-------FRDL 229

  Fly   123 EPEMGKV-VRQDKSGI-QKVRAKEIVPGDLVEVSVGDKIPADIRITHIYSTTLRIDQSILTGESV 185
            :.|..|: |:..::|. ||:...:::|||:|.:::||::|||......:|..  ||:|.|||||
plant   230 DKEKKKITVQVTRNGFRQKLSIYDLLPGDIVHLAIGDQVPADGLFLSGFSVV--IDESSLTGES- 291

  Fly   186 SVIKHTDAIPDPRAVNQDKKNILFSGTNVAAGKARGVVIGTGLSTAIGKIRTEMSETEEIKTPLQ 250
                      :|..||. :...|.|||.|..|..:.::...|:.|..||:...::|..:.:||||
plant   292 ----------EPVMVNA-QNPFLMSGTKVQDGSCKMMITTVGMRTQWGKLMATLTEGGDDETPLQ 345

  Fly   251 QKLDEFGEQLSKVISVICVAVWAINI-GHF-NDPAHGGSWIKGA------IYYFKIAVALAVAAI 307
            .||:.....:.|:.....|..:|:.: |.| ...:.|..|:...      :.||.|||.:.|.|:
plant   346 VKLNGVATIIGKIGLFFAVVTFAVLVQGMFMRKLSTGTHWVWSGDEALELLEYFAIAVTIVVVAV 410

  Fly   308 PEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSRMFIFDKV 372
            |||||..:|..||...::|....|:||.|.:.||:|..:.||||||||||||.|:|.:..|...|
plant   411 PEGLPLAVTLSLAFAMKKMMNDKALVRHLAACETMGSATTICSDKTGTLTTNHMTVVKSCICMNV 475

  Fly   373 E--GNDSSFLEFEMTGSTYEPI---------GEVFLN--GQRIKAADYDTLQELSTICIMCNDSA 424
            :  .|..|.|:.|:..|..:.:         |||.:|  |:.
plant   476 QDVANKGSSLQSEIPESAVKLLIQSIFNNTGGEVVVNKHGKT----------------------- 517

  Fly   425 IDYNEFKQAFEKVGEATETALIVLAEKLNSFSVNKSGLDRRSAAIACRGEIETKWKKEFTLE-FS 488
                      |.:|..||||::.|...|..                 :.:.|.|..|...:| |:
plant   518 ----------ELLGTPTETAILELGLSLGG-----------------KFQEERKSYKVIKVEPFN 555

  Fly   489 RDRKSMSSYCTPLKASRLGTGPKLFVKGAPEGVLERCTHARVGTTKVPLTSALKAKILALT-GQY 552
            ..:|.|.......:..|:    :...|||.|.||..|......:.:|........|.|.:| .::
plant   556 STKKRMGVVIELPEGGRM----RAHTKGASEIVLAACDKVVNSSGEVVPLDEESIKYLNVTINEF 616

  Fly   553 GTGRDTLRCLALAVAD--SPMKPDEMDLGDSTKFYQYEVNLTFVGVVGMLDPPRKEVFDSIVRCR 615
              ..:.||.|.||..|  ....||  |...::.|       |.||:||:.||.|..|.:|:..||
plant   617 --ANEALRTLCLAYMDIEGGFSPD--DAIPASGF-------TCVGIVGIKDPVRPGVKESVELCR 670

  Fly   616 AAGIRVIVITGDNKATAEAICRRIGVFAEDEDTTGKSYSGREFDDLSPTEQKAAVARSRLFSRVE 680
            .|||.|.::||||..||:||.|..|:..:|    |.:..|..|.:.:..|....:.:.::.:|..
plant   671 RAGITVRMVTGDNINTAKAIARECGILTDD----GIAIEGPVFREKNQEELLELIPKIQVMARSS 731

  Fly   681 PQHKSKIVEFLQ-SMNEISAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLADDNFSSI 743
            |..|..:|:.|: :.:|:.|:||||.||||||.:|:||:||| :||.|||.:|::::.|||||:|
plant   732 PMDKHTLVKQLRTTFDEVVAVTGDGTNDAPALHEADIGLAMGIAGTEVAKESADVIILDDNFSTI 796

  Fly   744 VSAVEEGRAIYNNMKQFIRYLISSNIGEVVSIFLTAALGLPEALIPVQLLWVNLVTDGLPATALG 808
            |:..:.||::|.|:::|:::.::.|:..:|..|.:|.|.....|..|||||||::.|.|.|.||.
plant   797 VTVAKWGRSVYINIQKFVQFQLTVNVVALVVNFSSACLTGSAPLTAVQLLWVNMIMDTLGALALA 861

  Fly   809 FNPPDLDIMEKPPRKADEGLISGWLFFRYMAIGFYVGAATVGAAAWWFV------------FSDE 861
            ..||:.::|::.|.......|:..::...:           |.|.:.|:            |..:
plant   862 TEPPNDELMKRLPVGRRGNFITNAMWRNIL-----------GQAVYQFIVIWILQAKGKAMFGLD 915

  Fly   862 GPKLSYWQLTHHLSCLGGGDEFKGVDCKIFSDPHAMTMALSVLVTIEMLNAMNSLSENQSLITMP 926
            ||..:....|...:|.        |.|::|::..:..|        |.::....:.:|...:.
plant   916 GPDSTLMLNTLIFNCF--------VFCQVFNEISSREM--------EEIDVFKGILDNYVFVV-- 962

  Fly   927 PWCNLWLIGSMALSFTLHFVILYVDVLSTVFQVTPLSAEEWITVMKFSIPVVLLDETLKFVARKI 991
                  :||:     |:.|.|:.::.|.|....|||:..:||    |||       .:.|:...|
plant   963 ------VIGA-----TVFFQIIIIEFLGTFASTTPLTITQWI----FSI-------FIGFLGMPI 1005

  Fly   992 ADG 994
            |.|
plant  1006 AAG 1008

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERCA	NP_726381.1	P-type_ATPase_SERCA	5..989	CDD:319778	289/1036 (28%)
ACA2	NP_195479.1	CaATP_NAI	5..49	CDD:432606
		ATPase-IIB_Ca	99..1014	CDD:273668	292/1043 (28%)