Protein Alignment Pp1-87B and PPP2CA

DIOPT Version :10

• Sequence 1: NP_524937.1
• Gene: Pp1-87B / 49260
• FlyBaseID: FBgn0004103
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_002706.1
• Gene: PPP2CA / 5515
• HGNCID: 9299
• Length: 309
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 139/295 - (47%)
• Similarity: 196/295 - (66%)
• Gaps: 10/295 - (3%)

  Fly     7 IDSIISRLLEVRGARPGKNVQLSEGEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLL 71
            :|..|.:|.|.:        ||||.:::.||.|::||...:..:.|:..|:.:|||:|||::||:
Human    10 LDQWIEQLNECK--------QLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLM 66

  Fly    72 RLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYD 136
            .||..||..|::||||:|||||||..|:||:.||:|.|::|.|...:||||||...|.::|||||
Human    67 ELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYD 131

  Fly   137 ECKRRY-SIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLTSMEQIRRIMRPTDVPDQGLLC 200
            ||.|:| :..:||.|||.|:.||:.|:||.:|||.||||||.:.:::.||.:.|..:||.:|.:|
Human   132 ECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMC 196

  Fly   201 DLLWSDPDKDTMGWGENDRGVSFTFGAEVVAKFLQKHEFDLICRAHQVVEDGYEFFAKRMLVTLF 265
            |||||||| |..|||.:.||..:|||.::...|...:...|:.||||:|.:||.:...|.:||:|
Human   197 DLLWSDPD-DRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIF 260

  Fly   266 SAPNYCGEFDNAGAMMSVDDTLMCSFQILKPADKR 300
            ||||||....|..|:|.:||||..||....||.:|
Human   261 SAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRR 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-87B	NP_524937.1	MPP_PP1_PPKL	6..296	CDD:277359	136/289 (47%)
PPP2CA	NP_002706.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	137/291 (47%)