DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp303a1 and CYP71B11

DIOPT Version :9

Sequence 1:	NP_001285977.1	Gene:	Cyp303a1 / 49165	FlyBaseID:	FBgn0001992	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_197894.1	Gene:	CYP71B11 / 832583	AraportID:	AT5G25120	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	531	Identity:	130/531 - (24%)
Similarity:	235/531 - (44%)	Gaps:	80/531 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFYTVI-WIFCATLLAILFGGVRKPKR-FPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQ 63
            ::|.:: ::|.:|:  |:....||.|: .||||...||:|:..|:.. :....||         :
plant     3 LWYIIVAFVFFSTI--IIVRNTRKTKKNLPPGPPRLPIIGNLHQLGS-KPHSSMF---------K 55

  Fly    64 YVNPYG-FYGLKIGKDKVVIAYTNDAISEMMTNEDID--GRPDGIFYRLRTFNSRLGVLLTD--- 122
            ....|| ...|:.|....|:|.|.:.:.|::...|.:  .||      ..|:.:||...|.|
plant    56 LSEKYGPLMALRFGSVSTVVASTPETVKEVLKTFDAECCSRP------YMTYPARLTYNLKDIGF 114

  Fly   123 ---GEMWVEQRR------FILRHLKNFGFAR----SGMMDIVHNEATCLLQ--DLKDKVLK-SGG 171
               .:.|.|.|:      :..:.:::|...|    :.::|.: .:|..|.:  :|..|::| ||.
plant   115 CPYTKYWREVRKMTVVELYTAKRVQSFQHTRKEEVASLVDFI-TQAASLEKPVNLNTKLMKLSGS 178

  Fly   172 KQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVG--ALFSHFPLLR 234
            ...|:       |:.:|     |.|.:.|....|:.|         ..:::||  |...:||::.
plant   179 VICRV-------VFGIN-----LKGSKLENLYEEVIQ---------GTMEVVGSFAAADYFPIIG 222

  Fly   235 FIAPNFSGYNGFVES-HRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKGMF--S 296
            .|....:|.:...|. .:::..|..:.|: |.|..::..:  |::|..|: .:.|..|.|.|  :
plant   223 RIIDRITGLHSKCEKIFKAMDAFFDQSIK-HHLEDESIKD--DIIDLLLK-MERGEIELGEFQLT 283

  Fly   297 DQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVV-GLERIPEWSRDRTKLP 360
            ..:...|..::..||.:|:.:.:.:...:|:..|.:.::|..|::||: ..:.|.|  .|..:|.
plant   284 RDNTKGILFNILNAGIDTSAQVMTWVMTYLISNPRVMKKAQAEVREVIKNKDDIIE--EDIERLE 346

  Fly   361 YCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDR 425
            |.:.:..|..|:..|....||..|..|.::.||:|||.|.:......:..||..:.|||:|.|:|
plant   347 YLKMVVKETFRVLPLVPLLIPREASKDVKIGGYDIPKKTWIHVNIWAIHRNPNVWKDPEAFIPER 411

  Fly   426 YLFDGHLK---LPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLEGA 487
            :: |..:.   |...|.|||.||..|.|..:|...:.:....:|..|......|...|:|.||.:
plant   412 FM-DNQIDYKGLNFEFLPFGSGRRMCPGIGMGMALVHLTLINLLYRFDWKLPEGMEVEDVDLEES 475

  Fly   488 TAAVKPYDIML 498
            ...|.|..:.|
plant   476 YGLVCPKKVPL 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_001285977.1	p450	28..480	CDD:278495	116/482 (24%)
CYP71B11	NP_197894.1	CYP71-like	59..486	CDD:410695	112/461 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000