Protein Alignment Cyp303a1 and cyp2ad6

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001076405.1
• Gene: cyp2ad6 / 799957
• ZFINID: ZDB-GENE-041001-157
• Length: 492
• Species: Danio rerio
• Alignment Length: 502
• Identity: 139/502 - (27%)
• Similarity: 233/502 - (46%)
• Gaps: 41/502 - (8%)

  Fly     7 WIFCATLLAILFGGVR--KPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYG 69
            |:|....|.:|...:|  .|..|||||...||:|:..        ..:..|.:|    |.:..||
Zfish    15 WLFLTCFLLLLIDLIRNKNPANFPPGPWPLPILGNVF--------TDVNYKTVD----QLIEKYG 67

  Fly    70 -FYGLKIGKDKVVIAYTNDAISEMM--TNEDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRR 131
             .:.::||.||:|.......:.:::  ..|:...||....:  .|.....|:...:|..|.:.::
Zfish    68 NIFSVRIGSDKIVYVSGFKMVKDVLITQGENFTDRPVSPLF--DTLYKGRGLSFNNGYSWRKHQQ 130

  Fly   132 FILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHD-LTSV--YVLNTLWCM 193
            |.:.||||||..|..:.:  :|:..|..       |....|:.:....| |..:  .|.|.:..:
Zfish   131 FSMSHLKNFGEGRKTLEE--NNQRECYF-------LCGAFKEEQGRPFDPLVKINNAVANVIGFL 186

  Fly   194 LSGRRYEPGSPEITQLLETFFE-LFKNIDMVGALFSHFP-LLRFIAPNFSGYNGFVESHRSLYTF 256
            :.|.|||.......:.|:...| :|....:...|:..|| :::::.   ..:...:.:::.|..|
Zfish   187 VFGHRYEYSDVNFQKRLQMSAESVFLTGSVWNQLYDAFPGIMKWVP---GPHQTIISNYQKLANF 248

  Fly   257 MSKEIELHRLTYKNYDEPRDLMDSYL-RAQDEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLG 320
            :.::||.|:..: :...|||.:|:|| .|:.:.||.:..|:..||:...:|:|..|:|||..:|.
Zfish   249 LEEKIEQHKPDW-DISNPRDYIDAYLTEAEKKKNDTEAGFTVGSLVWSMVDLFEGGTETTTNTLR 312

  Fly   321 FCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAV 385
            :..:.|:..|:||::...||.||:| .|:|..| |:..:.|..|...|.:|...|....:...|.
Zfish   313 WALLFLIKYPDIQKKVQAEIDEVIG-SRLPSMS-DKANMHYLNAFIHEVLRRANLVPLNMARVAK 375

  Fly   386 CDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGHLKLPEAFNPFGFGRHRCM 449
            .||.|.||.|.|.|::|.....:|.:..::..|::|||..:| .:||.....||..|..|:.:|.
Zfish   376 KDTTLGGYFITKGTVMITNLTSVLYDKQEWETPDAFNPKHFLDSEGHFCRRNAFFAFSAGKRQCP 440

  Fly   450 GDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLEGATAAVKPYDI 496
            |:.|....||:|.|.:||.|......|:.|......|.|.|..||.|
Zfish   441 GEYLAHLELFIFLTILLQTFSFSPPDGEEPSLDSQVGFTQAPLPYKI 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	121/437 (28%)
cyp2ad6	NP_001076405.1	cytochrome_P450	66..487	CDD:477761	121/437 (28%)