Protein Alignment Cyp303a1 and Cyp2d40

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_076112.2
• Gene: Cyp2d40 / 71754
• MGIID: 1919004
• Length: 338
• Species: Mus musculus
• Alignment Length: 348
• Identity: 103/348 - (29%)
• Similarity: 163/348 - (46%)
• Gaps: 43/348 - (12%)

  Fly   180 DLTSVYVLNTLWCMLSG---------RRYEPGS---PEITQLLETF-----FELFKNIDMVGALF 227
            ||..|.:...::.:|..         .||.||.   |.:..||:..     :..:|.:.|
Mouse     8 DLWPVAIFTVIFILLVDLLHRRQRWTSRYPPGPVPWPVLGNLLQVDLDNMPYSFYKVVKM----- 67

  Fly   228 SHFPLLRFIAPN-----FSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQD- 286
              ||::..| |.     |.|...|:       |.:.|.:..|:.|:.....||||.|:::...:
Mouse    68 --FPIVLRI-PGLADKIFPGQKTFL-------TMVDKLVTEHKRTWDPDQPPRDLTDAFMAEMET 122

  Fly   287 -EGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIP 350
             :||.|.. |::.:|..:.||:|..|..||:.:|.:..:.::|.|::|.|..:||.||:|..|.|
Mouse   123 AKGNPESS-FNEANLRLVVLDLFGGGIVTTSATLTWALLLMILHPDVQRRVQEEIDEVIGQARRP 186

  Fly   351 EWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDF 415
            |.: |:.::||..|:..|..|...:....:|||..||..:.|:.|||.|.:|.....:|.:...:
Mouse   187 EMA-DQARMPYTNAVIHEVQRFADIAPMTLPHRTSCDIEVQGFLIPKGTTLICNLSSVLKDETVW 250

  Fly   416 PDPESFNPDRYL-FDGHLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQ-V 478
            ..|..|.|:.:| ..||...||||.||..||..|:|:.|.|..||:|.|.:||.|......|| :
Mouse   251 EKPLRFYPEHFLDAQGHFVKPEAFMPFSAGRRACLGEPLVRMELFLFFTCLLQRFSFSVPDGQPL 315

  Fly   479 PEEVPLEGATAAVKPYDIMLVAR 501
            |.:..:.....:..||.:..|.|
Mouse   316 PSDYGIYSMVVSPAPYQLCAVVR 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	101/341 (30%)
Cyp2d40	NP_076112.2	cytochrome_P450	<63..333	CDD:477761	90/286 (31%)