Protein Alignment Cyp303a1 and cyp2k19

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001073172.1
• Gene: cyp2k19 / 562304
• ZFINID: ZDB-GENE-091211-1
• Length: 502
• Species: Danio rerio
• Alignment Length: 515
• Identity: 146/515 - (28%)
• Similarity: 245/515 - (47%)
• Gaps: 53/515 - (10%)

  Fly    12 TLLAILF---------GGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVF---ARQY 64
            ||||.|.         .|.:|..:.||||...|::|:.|.:...|        ..|.|   ::.|
Zfish    15 TLLAALLLFLVLYLVSSGSQKEGKEPPGPKPLPLLGNLLTLDLTR--------AFDTFFELSKTY 71

  Fly    65 VNPYGFYGLKIGKDKVVIAYTNDAISEMMTN--EDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWV 127
            .|.:..:   :|..|.|:......:.|.:.|  |....|..|..:|:  .|...|:|.::||.|.
Zfish    72 GNVFQVF---LGPRKTVVLVGYKTVKEALVNYAEQFGDREIGPGFRI--MNDEHGILFSNGENWK 131

  Fly   128 EQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLT---SVYVLNT 189
            |.|||.|.:|::||..:.|..:.:..|    :..||.:..|..||.     .|.|   :..|.|.
Zfish   132 EMRRFALSNLRDFGMGKRGSEEKIIEE----IHHLKGEFDKFEGKP-----FDTTQPVNYAVSNI 187

  Fly   190 LWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHF-PLLRFIAPNFSGYNGFVESHRSL 253
            :..::.|.|:|...|:.|::::...|   |:.:.|::...| .:..::.|........||:....
Zfish   188 ISSIVYGSRFEYTDPQFTEMVDRANE---NVRVGGSVSMWFHEMFPWVGPFLKSKRIIVENIIQS 249

  Fly   254 YTFMSKEIELHRLTYKNYDEPRDLMDSYL--RAQDEGNDEK-GMFSDQSLLAICLDMFLAGSETT 315
            ...|:|.|.. .|...|.::||..:||:|  :..||.:.:| ..|.:::|:....::|:||::||
Zfish   250 RAQMTKLITA-LLETLNPNDPRGFVDSFLTRKLSDEKSGKKDSYFHEENLIMTVTNLFVAGTDTT 313

  Fly   316 NKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGI 380
            ..:|.:..|.:...|:||:|..:||..|:| .|.|. ..||.||||.:|:..|..|:..:....:
Zfish   314 GTTLRWGLMLMAKYPQIQDRVQEEIDRVIG-GRQPV-VEDRKKLPYTDAVIHEIQRLANIVPLSL 376

  Fly   381 PHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFD-GHLKLPEAFNPFGFG 444
            ||:...|...:||.|.|.|.|:.....:|.:..::..|.||.|:.:|.: |.....:||.||..|
Zfish   377 PHKTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFIPFSAG 441

  Fly   445 RHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLE---GATAAVKPYDIMLVAR 501
            |..|:|:.|.|..||:|.|::||:::....||...:|:.|:   |.|....|:.:..:.|
Zfish   442 RRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVGITLNPSPHKLCAIRR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	126/440 (29%)
cyp2k19	NP_001073172.1	cytochrome_P450	71..496	CDD:477761	128/444 (29%)