Protein Alignment Cyp303a1 and cyp2k8

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001124095.1
• Gene: cyp2k8 / 561462
• ZFINID: ZDB-GENE-080721-19
• Length: 507
• Species: Danio rerio
• Alignment Length: 501
• Identity: 137/501 - (27%)
• Similarity: 236/501 - (47%)
• Gaps: 62/501 - (12%)

  Fly    28 PPGPAWYPIVGS--ALQVSQLRCRLGMFCKVIDVFARQYVNPYG-FYGLKIGKDKVVIAYTNDAI 89
            ||||...|::|:  .|.:..|...|....|           .|| .:.:.:|:.|||:......:
Zfish    40 PPGPKPLPLLGNLHTLDLKNLHVSLWELSK-----------KYGPVFKVHLGRKKVVVLAGYKTV 93

  Fly    90 SEMMTNEDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNE 154
            .:.:.|:..:.....|....:..|...|::..:||.|...|||.|..|::||..:....:.:.:|
Zfish    94 KQALVNQAEEFGERDITPIFQDCNQGQGIVFANGERWRTMRRFALSTLRDFGMGKKLSEEKIVDE 158

  Fly   155 ATCLLQDLKDKVLKSGGKQTRIEMHDLT---SVYVLNTLWCMLSGRRYEPGSPEITQLLETFFEL 216
            .    :.|::..:|..|     :..|.|   :..|.|.:..::.|:|:|...|....::.   :.
Zfish   159 T----RYLREVFMKFEG-----QPFDTTQPVNYAVSNIISAIVYGKRFEYEDPAFQDMVN---KA 211

  Fly   217 FKNIDMVG-ALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYK----------N 270
            ..||.|:| |:...:.:..|:.|       ::::.|.|    .|.:|..|...:          |
Zfish   212 NMNIRMIGSAVIQIYNMCPFLGP-------WIKTWRQL----MKNMESTRRQIQTLADVLQETLN 265

  Fly   271 YDEPRDLMDSYL-RAQD--EGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEI 332
            ..:.|.|:||:| |.|:  |..::...|:||:||....::|.||::||..:|.:..|.:...|:|
Zfish   266 PLDCRGLIDSFLIRKQNIQETGEKDSSFNDQNLLITVSNLFAAGTDTTGTTLRWGLMLMAKYPQI 330

  Fly   333 QERAFQEIKEVV-GLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIP 396
            |:|..:||.:|: |.|.:.|   ||..|||.:|:..|..|:..:....:||:..||...:||.|.
Zfish   331 QDRVQEEIDQVLGGREPVAE---DRKNLPYTDAVIHETQRLANILPLNLPHKTSCDVTFNGYFIK 392

  Fly   397 KDTMVIACFRGMLINPVDFPDPESFNPDRYLFD-GHLKLPEAFNPFGFGRHRCMGDLLGRQNLFM 460
            |.|.|:.....:|.:..::..|::|||..:|.: |.|...:||.||..||..|:|:.|.|..||:
Zfish   393 KGTCVLPLLTSVLRDETEWETPDTFNPQHFLDEKGQLIKRDAFMPFSAGRRACLGESLARMELFL 457

  Fly   461 FTTTVLQNFKMVAIPGQVPEEV---PLEGATAAVKPYDIMLVAREQ 503
            |.|::||.|:....||...:|:   |:.|.|....|:.:..|.|.:
Zfish   458 FFTSLLQYFRFSPPPGASEDELDLTPVVGLTLNPSPHKLCAVIRAE 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	125/450 (28%)
cyp2k8	NP_001124095.1	cytochrome_P450	71..496	CDD:477761	125/450 (28%)