Protein Alignment Cyp303a1 and Cyp2c54

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_996260.1
• Gene: Cyp2c54 / 404195
• MGIID: 3642960
• Length: 490
• Species: Mus musculus
• Alignment Length: 514
• Identity: 142/514 - (27%)
• Similarity: 243/514 - (47%)
• Gaps: 66/514 - (12%)

  Fly     5 VIWIFCATLLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYG 69
            |:.:.|..||::......:.| .||||...||:|:.||:.     :...|:.....:|.|...|.
Mouse     8 VLTLSCLFLLSLWRQSYERGK-LPPGPTPLPIIGNILQID-----VKDICQSFTNLSRVYGPVYT 66

  Fly    70 FYGLKIGKDKVVIAYTNDAISEMMTNE-DI-DGRPDGIFYRLRTFN---SRLGVLLTDGEMWVEQ 129
            .|   :|:...|:.:..:|:.|.:.:. |: .||.     ||..|:   :.:|:..::|.:|...
Mouse    67 LY---LGRKPTVVLHGYEAVKEALVDHGDVFAGRG-----RLPVFDKATNGMGIGFSNGSVWKNT 123

  Fly   130 RRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVL-----NT 189
            |.|.|..|:|.|..:..:.|.|..||.||:::|:    |:.|...     |.|  ::|     |.
Mouse   124 RHFSLMTLRNLGMGKRSIEDRVQEEARCLVEELR----KTNGSPC-----DPT--FILGCAPCNV 177

  Fly   190 LWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVG-ALFSHFPLLRFIAPNFSGYNGFVESHRSL 253
            :..::...|::....:...|||...|:.|.:.... .:.:.||.|....|  ..:|.|.:::..:
Mouse   178 ICSIIFQDRFDYKDRDFLNLLEKLDEISKILSTPWLQVCNTFPALLDYCP--GSHNQFFKNYAYI 240

  Fly   254 YTFMSKEIELHRLTYKNYDE--PRDLMDSYLRAQDEGNDEKGMFSDQSLLAICL-DMFLAGSETT 315
            ..|:.::|..|:   ::.|.  |||.:|.:|....:.:|...:.::...|||.: |:|:.|:|:.
Mouse   241 KNFLLEKIREHK---ESLDVTIPRDFIDYFLIKGAQEDDNHPLKNNFEHLAITVTDLFIGGTESM 302

  Fly   316 NKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGI 380
            :.:|.:..:.|:..|.:..:..:||:.|:|..|.| ..:||:.:||..|:..|..|...|....:
Mouse   303 STTLRYALLLLLKYPHVTAKVQEEIEHVIGKHRRP-CMQDRSHMPYTNAMIHEVQRFIDLVPNNL 366

  Fly   381 PHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFD-GHLKLPEAFNPFGFG 444
            ||...||.:...|.|||.|.||.....:|.:..:||:||.|:|..:|.: |..|..:.|.||..|
Mouse   367 PHEVTCDIKFRNYFIPKGTTVITSLSSVLRDSKEFPNPEKFDPGHFLDENGKFKKSDYFMPFSTG 431

  Fly   445 RHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLEGATAAVKPYDI----MLV 499
            :..|.|:.|.|..||:|.|::||||.:          .||      |.|.||    ||:
Mouse   432 KRICAGEGLARMELFLFLTSILQNFNL----------KPL------VHPKDIDITPMLI 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	121/442 (27%)
Cyp2c54	NP_996260.1	CYP2C-like	61..485	CDD:410758	126/455 (28%)