Protein Alignment Cyp303a1 and cyp2aa3

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_938183.2
• Gene: cyp2aa3 / 386638
• ZFINID: ZDB-GENE-031030-8
• Length: 496
• Species: Danio rerio
• Alignment Length: 525
• Identity: 146/525 - (27%)
• Similarity: 239/525 - (45%)
• Gaps: 77/525 - (14%)

  Fly     8 IFCATLLAILFGGVR---KPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYG 69
            :|...::.:||...|   ..:|.||||...|.||:          :..|.|          ||.|
Zfish    17 LFLGLIILVLFEIFRIHSYKRRTPPGPTPLPFVGT----------IPHFLK----------NPLG 61

  Fly    70 F------YG----LKIGKDKVVIAYTNDAISEMMTNEDIDGRP---------DGIFYRLRTFNSR 115
            |      ||    :.:|:...:...|.....|.:..:...|:|         .|....:.|||
Zfish    62 FIRSMSQYGDMSTMYLGRKPAIFLNTIQLAKETLVQDTFSGKPYLPVIEWISKGFGIAMVTFN-- 124

  Fly   116 LGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHD 180
                    ..|.:||||.|..|||||..:..:.|.|..|:..|:.::    ||..||.  ::.|.
Zfish   125 --------HSWRQQRRFALHTLKNFGLGKKSVEDRVLEESRYLIAEM----LKDEGKP--VDPHH 175

  Fly   181 LTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSH-FPLLRFIAPNFSGYN 244
            .....|.|.:..::.|.|:|..:.....||:.   |.:.|.:.|:.... |.|:.|| .:|.|.:
Zfish   176 PIQNAVSNIICSIVFGDRFEYNNKRFEYLLKM---LNETIMLAGSASGRIFNLVPFI-KHFPGPH 236

  Fly   245 GFVESHR-SLYTFMSKEIELHRLTYKNYDEPRDLMDSY-LRAQDEGNDEKGMFSDQSLLAICLDM 307
            ..::.:. .|..|:..|:|.||.|. :...|||.:|:| |..:.:..::...|.:.:|||...|:
Zfish   237 QKIKKNTDDLLIFLGDEVEEHRKTL-DPGSPRDFIDAYLLEIEKQKFNKDSTFHEGNLLASAGDL 300

  Fly   308 FLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRM 372
            |:||::||..::.:..:.|:..|::|||..:||.:|:|.:|:|... ||.:|||    ||..|..
Zfish   301 FMAGTDTTETTIRWGLLFLIQNPDVQERCHEEIVQVLGYDRLPSMD-DRDRLPY----TLATVHE 360

  Fly   373 FMLHTFGIP---HRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFDGHLKL 434
            ...:...||   |..:..|:|.||.||:.|.::...:.:..:...:..|:||||:.:|.|.|...
Zfish   361 IQRYGNIIPILIHETILPTKLQGYSIPQGTTIVTNIQAIFSSKDHWKHPDSFNPENFLEDRHFIK 425

  Fly   435 PEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLEGATAAV-KPYDIML 498
            ||:|..|..|...|:|::|.|..||:|.|::||.......|...|  :.::|....| .|....:
Zfish   426 PESFIMFSLGPRSCLGEILARTELFLFITSLLQRIHFSWPPDAKP--IDMDGIFGLVHSPQAFNV 488

  Fly   499 VAREQ 503
            :.|.:
Zfish   489 ICRSR 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	129/453 (28%)
cyp2aa3	NP_938183.2	cytochrome_P450	69..488	CDD:477761	127/446 (28%)