Protein Alignment Cyp303a1 and Cyp2b3

DIOPT Version :10

• Sequence 1: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_775416.1
• Gene: Cyp2b3 / 286953
• RGDID: 628627
• Length: 491
• Species: Rattus norvegicus
• Alignment Length: 519
• Identity: 146/519 - (28%)
• Similarity: 244/519 - (47%)
• Gaps: 51/519 - (9%)

  Fly     4 TVIWIFCATLLAILF----GGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQY 64
            |.:.:..|.||:.|.    |..:.....||||...|::|:.||:.:     |.|.|.......::
  Rat     3 TSVLLLLAVLLSFLLFLVRGHAKVHGHLPPGPRPLPLLGNLLQMDR-----GGFRKSFIQLQEKH 62

  Fly    65 VNPYGFYGLKIGKDKVVIAYTNDAISEMMTN--EDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWV 127
            .:.:..|   .|...||:......|.|.:.:  |...||  ||...|:......||...:.|.|.
  Rat    63 GDVFTVY---FGPRPVVMLCGTQTIREALVDHAEAFSGR--GIIAVLQPIMQEYGVSFVNEERWK 122

  Fly   128 EQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWC 192
            ..||..:..:::||..:..:.|.:..||.||:::||:.      :...::...|......|.:..
  Rat   123 ILRRLFVATMRDFGIGKQSVEDQIKEEAKCLVEELKNH------QGVSLDPTFLFQCVTGNIICS 181

  Fly   193 MLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGFVE----SHRSL 253
            ::.|.|::....:..:||:..:..|..|.            .|.:..|..|:.|::    .||.:
  Rat   182 IVFGERFDYRDRQFLRLLDLLYRTFSLIS------------SFSSQMFEVYSDFLKYFPGVHREI 234

  Fly   254 Y-------TFMSKEIELHRLTYKNYDEPRDLMDSY-LRAQDEGNDEKGMFSDQSLLAICLDMFLA 310
            |       .::...:|.||.|. :.:.|||.:|:: |..:.|..:....|...:|:...|.:|||
  Rat   235 YKNLKEVLDYIDHSVENHRATL-DPNAPRDFIDTFLLHMEKEKLNHYTEFHHWNLMISVLFLFLA 298

  Fly   311 GSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFML 375
            |:|:|:.:|.:.|:.::..|.:.|:..:||.:|:|.:|:|... ||:|:||.||:..|..|...:
  Rat   299 GTESTSNTLCYGFLLMLKYPHVAEKVQKEIDQVIGSQRVPTLD-DRSKMPYTEAVIHEIQRFSDV 362

  Fly   376 HTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGHLKLPEAFN 439
            ...|:|.|...||...||.:||:|.|.......|.:|..|..|::|||:.:| .:|.||..|||.
  Rat   363 SPMGLPCRITKDTLFRGYLLPKNTEVYFILSSALHDPQYFEQPDTFNPEHFLDANGALKKCEAFM 427

  Fly   440 PFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVA-IPGQVPEEVPLEGATAAVKP-YDIMLVAR 501
            ||..|:..|:|:.:.|..||:|.||:|||:.:.: :.....:..|.|...|.|.| |.|..|||
  Rat   428 PFSIGKRMCLGEGIARSELFLFFTTILQNYSVSSPVDPNTIDMTPKESGLAKVAPVYKICFVAR 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	125/444 (28%)
Cyp2b3	NP_775416.1	CYP2B	62..486	CDD:410765	125/448 (28%)