Protein Alignment Src64B and EDR1

DIOPT Version :10

• Sequence 1: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_563824.1
• Gene: EDR1 / 837393
• AraportID: AT1G08720
• Length: 933
• Species: Arabidopsis thaliana
• Alignment Length: 590
• Identity: 135/590 - (22%)
• Similarity: 228/590 - (38%)
• Gaps: 148/590 - (25%)

  Fly    48 GQKH----NNGGSLDSRYTPDPNHRGPLKIGGKGGVDIIRPRTTPT--------------GVPGV 94
            |..|    |...|||.|...:.......|:|....:|...|.:..:              |..|.
plant   366 GSSHSSMANYSSSLDRRTEAERTDSSYPKVGPLRNIDYSSPSSVTSSTQLENNSSTAIGKGSRGA 430

  Fly    95 VLK--RVVVALYDYKSRDESDLSFM---------KG-DRMEV--------IDDTESD-------- 131
            :::  |..:.:..|....|.|...:         || |::.:        :||....
plant   431 IIECSRTNMNIVPYNQNSEEDPKNLFADLNPFQNKGADKLYMPTKSGLNNVDDFHQQKNNPLVGR 495

  Fly   132 -----WWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPR-GTFLVRP 190
                 .|:              |:...|.....|:.:.||:|.|       ...:|| |......
plant   496 SPAPMMWK--------------NYSCNEAPKRKENSYIENLLPK-------LHRDPRYGNTQSSY 539

  Fly   191 SEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIAT-NQTFPSLQALVMAYSKENALGL-- 252
            :..:.||...|.....|...:      :.|:.....:.:| ||..||: ...|..:..|.|.|
plant   540 ATSSSNGAISSNVHGRDNVTF------VSPVAVPSSFTSTENQFRPSI-VEDMNRNTNNELDLQP 597

  Fly   253 -------------CHI----------LSRPCPKPQPQMWD--------------LGPELRD---- 276
                         .||          :|..|   .|::.|              ..|::.|
plant   598 HTAAVVHGQQNDESHIHDHRKYTSDDISTGC---DPRLKDHESTSSSLDSTSYRNDPQVLDDADV 659

  Fly   277 -KYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAA---FLQEAAIMKKFRH 337
             :.|||.:::.:..::|.|::|||::..|..: :||||...:...|.||   |..|..||::.||
plant   660 GECEIPWNDLVIAERIGLGSYGEVYHADWHGT-EVAVKKFLDQDFSGAALAEFRSEVRIMRRLRH 723

  Fly   338 NRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFED--LIYIATQVASGMEYLESK- 399
            ..:|......::...:.||.|::.:|||...|.....   |.::  .|.:|..||.||..|.:.
plant   724 PNVVFFLGAVTRPPNLSIVTEFLPRGSLYRILHRPKS---HIDERRRIKMALDVAMGMNCLHTST 785

  Fly   400 -QLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSD 463
             .::||||...|:|:..|...|:.||||:|:..:.....|..:..| :|.|||.:.....:.|.|
plant   786 PTIVHRDLKTPNLLVDNNWNVKVGDFGLSRLKHNTFLSSKSTAGTP-EWMAPEVLRNEPSNEKCD 849

  Fly   464 VWSYGILLMELFTYGQVPYPGMHSREVIENI---ERGFRMPKPTNHYFPDNIYQLLLQCWDAVPE 525
            |:|:|::|.||.|. ::|:.||:..:|:..:   .|...:||..:..    :.:::|:||...|.
plant   850 VYSFGVILWELATL-RLPWRGMNPMQVVGAVGFQNRRLEIPKELDPV----VGRIILECWQTDPN 909

  Fly   526 KRPTF 530
            .||:|
plant   910 LRPSF 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH2_Src_family	158..259	CDD:199827	25/127 (20%)
		PTKc_Src_like	289..538	CDD:270630	77/252 (31%)
		SH3_Src_like	99..150	CDD:212779	9/81 (11%)
EDR1	NP_563824.1	EDR1	129..326	CDD:433922
		STKc_MAP3K-like	675..921	CDD:270901	77/250 (31%)