Protein Alignment Src64B and map3k10

DIOPT Version :10

• Sequence 1: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_689424.4
• Gene: map3k10 / 560932
• ZFINID: ZDB-GENE-050419-112
• Length: 1062
• Species: Danio rerio
• Alignment Length: 453
• Identity: 119/453 - (26%)
• Similarity: 177/453 - (39%)
• Gaps: 143/453 - (31%)

  Fly   102 ALYDYKSRDESDLSFMKGDRMEVID-----DTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSED 161
            |::||::..:.:|:..:||.:||:.     ..:..||  ......:.|:.|.|:|.:..|
Zfish    84 AVFDYEATADEELTLRRGDLLEVLSKDSKVSGDEGWW--TGKIQDKVGIFPCNYVTQRDS----- 141

  Fly   162 WFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGY 226
                                                                             
Zfish   142 ----------------------------------------------------------------- 141

  Fly   227 YIATNQTFPSL--QALVMAYSKENALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLR 289
                  ::|:|  :|||...|                               ..||...|::|..
Zfish   142 ------SYPALPPEALVGGDS-------------------------------PLEIDFLELRLEE 169

  Fly   290 KLGRGNFGEVFYGKWRNSIDVAVKTLR----EGTMSTAAFL-QEAAIMKKFRHNRLVALYAVCSQ 349
            .:|.|.||:|:.|.|| :.:||||..|    |...:||..: |||.:....||..::||..||.:
Zfish   170 VIGAGGFGKVYKGVWR-AEEVAVKAARQDPDEDISATAENVRQEARLFWMLRHRNIIALRGVCLR 233

  Fly   350 EEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESK---QLIHRDLAARNV 411
            |..:.:|.||...|:|...|.   |:.:....|:..|.|:|:||:||.::   .:|||||.:.|:
Zfish   234 EPNLCLVMEYARGGALNRALA---GKKVPPRVLVNWAVQIATGMDYLHNQTFVPIIHRDLKSSNI 295

  Fly   412 LIGE--------NNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYG 468
            ||.|        ....||.||||||   :.....|..:.....|.|||.|....||..|||||:|
Zfish   296 LILEPVERDDLSGKTLKITDFGLAR---EWHRTTKMSAAGTYAWMAPEVIKLSLFSKSSDVWSFG 357

  Fly   469 ILLMELFTYGQVPYPGMHSREVIENIERG-FRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTF 530
            :||.||.| |:|||..:.:..|...:... ..:|.|:.  .|:...|||.:||...|..||.|
Zfish   358 VLLWELLT-GEVPYREIDALAVAYGVAMNKLTLPIPST--CPEAFAQLLGECWCPNPRGRPAF 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH2_Src_family	158..259	CDD:199827	6/102 (6%)
		PTKc_Src_like	289..538	CDD:270630	94/259 (36%)
		SH3_Src_like	99..150	CDD:212779	12/52 (23%)
map3k10	XP_689424.4	SH3_MLK1-3	81..138	CDD:212992	14/55 (25%)
		STKc_MLK2	170..427	CDD:271050	94/258 (36%)