Protein Alignment Src64B and Map3k13

DIOPT Version :10

• Sequence 1: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001014000.2
• Gene: Map3k13 / 303823
• RGDID: 1561227
• Length: 958
• Species: Rattus norvegicus
• Alignment Length: 317
• Identity: 102/317 - (32%)
• Similarity: 154/317 - (48%)
• Gaps: 48/317 - (15%)

  Fly   260 CPKPQPQMW---------DLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTL 315
            |.:|   :|         |...:.:|.:|:|..||..|:.||.|..|.||.||:| :.:||:|.:
  Rat   137 CLRP---VWNIIGKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFR-AEEVAIKKV 197

  Fly   316 REGTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFE 380
            ||...:....|      :|.:|..::|...||:|.....|:.||.:.|.|.:.||.  ||.:...
  Rat   198 REQNETDIKHL------RKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRA--GRKITPR 254

  Fly   381 DLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPV 445
            .|:..:|.:||||.||...::|||||.:.|||:...:..||.|||.::.::|..  .|......|
  Rat   255 LLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDKS--TKMSFAGTV 317

  Fly   446 KWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENI-ERGFRMPKPTNHYFP 509
            .|.|||.|.....|.|.|:||:|::|.||.| |::||..:.|..:|..: .....:|.|:.  .|
  Rat   318 AWMAPEVIRNEPVSEKVDIWSFGVVLWELLT-GEIPYKDVDSSAIIWGVGSNSLHLPVPST--CP 379

  Fly   510 DNIYQLLLQCWDAVPEKRPTF-EFLNH---------------YFESFSVTSEVPYRE 550
            |....|:.|.|.:.|..||:| :.|.|               ||:     |:..:||
  Rat   380 DGFKILMKQTWQSKPRNRPSFRQTLMHLDIASADVLATPQETYFK-----SQAEWRE 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH2_Src_family	158..259	CDD:199827
		PTKc_Src_like	289..538	CDD:270630	88/265 (33%)
		SH3_Src_like	99..150	CDD:212779
Map3k13	NP_001014000.2	STKc_MAP3K12_13	174..410	CDD:270961	87/249 (35%)