| Sequence 1: | NP_001286937.1 | Gene: | Src64B / 48973 | FlyBaseID: | FBgn0262733 | Length: | 553 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001167538.1 | Gene: | FGFR1 / 2260 | HGNCID: | 3688 | Length: | 853 | Species: | Homo sapiens |
| Alignment Length: | 648 | Identity: | 181/648 - (27%) |
|---|---|---|---|
| Similarity: | 264/648 - (40%) | Gaps: | 155/648 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 4 KCCSK----------RQDQELALAYPTGGYKKSDYTFG--QTHINSSGGGNMGGVLGQKHNNGGS 56
Fly 57 LDSRYTPDPNHRGPLKIGGKGGVDIIRPRTTPTGVPGVVLKRVVVALYDYKSRDESDLSFMKGDR 121
Fly 122 MEVIDDTES--DWWRVVNLTTRQEG--LIPLNFVAEERSVNSEDWFFE-----NVLRKEADK--- 174
Fly 175 -----------------LLLAEENP---------------RGTFLVRPSEHNPNGYSL----SVK 203
Fly 204 DWEDGRGYHVKHYRIKPLD-------------NGGYYIATNQTFPSLQALVMAYSKENALGLCHI 255
Fly 256 LSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYG--------KWRNSIDVAV 312
Fly 313 KTLREGT--MSTAAFLQEAAIMKKF-RHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFL--REG 372
Fly 373 DG------------RYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFG 425
Fly 426 LARVIADDEYCPK-QGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSRE 489
Fly 490 VIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESF-SVTSEVPYREV 551 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Src64B | NP_001286937.1 | SH2_Src_family | 158..259 | CDD:199827 | 25/157 (16%) |
| PTKc_Src_like | 289..538 | CDD:270630 | 112/274 (41%) | ||
| SH3_Src_like | 99..150 | CDD:212779 | 11/54 (20%) | ||
| FGFR1 | NP_001167538.1 | IgI_1_FGFR | 58..151 | CDD:409362 | |
| Ig strand A | 58..61 | CDD:409362 | |||
| Ig strand A' | 73..79 | CDD:409362 | |||
| Ig strand B | 82..92 | CDD:409362 | |||
| Ig strand C | 96..101 | CDD:409362 | |||
| Ig strand C' | 104..106 | CDD:409362 | |||
| Ig strand D | 111..115 | CDD:409362 | |||
| Ig strand E | 118..123 | CDD:409362 | |||
| Ig strand F | 129..138 | CDD:409362 | |||
| Ig strand G | 141..151 | CDD:409362 | |||
| IgI_2_FGFR | 184..278 | CDD:409443 | 16/72 (22%) | ||
| Ig strand A | 184..187 | CDD:409443 | |||
| Ig strand A' | 195..200 | CDD:409443 | |||
| Ig strand B | 204..212 | CDD:409443 | 2/3 (67%) | ||
| Ig strand C | 218..223 | CDD:409443 | 0/4 (0%) | ||
| Ig strand C' | 226..228 | CDD:409443 | 0/1 (0%) | ||
| Ig strand D | 237..240 | CDD:409443 | 2/2 (100%) | ||
| Ig strand E | 244..249 | CDD:409443 | 0/4 (0%) | ||
| Ig strand F | 258..265 | CDD:409443 | 1/9 (11%) | ||
| Ig strand G | 268..278 | CDD:409443 | 3/9 (33%) | ||
| Ig | 286..390 | CDD:472250 | 21/119 (18%) | ||
| Ig strand B | 304..308 | CDD:409353 | 2/7 (29%) | ||
| Ig strand C | 317..321 | CDD:409353 | 0/3 (0%) | ||
| Ig strand E | 355..359 | CDD:409353 | 1/3 (33%) | ||
| Ig strand F | 369..374 | CDD:409353 | 0/4 (0%) | ||
| Ig strand G | 382..385 | CDD:409353 | 0/2 (0%) | ||
| PTKc_FGFR1 | 495..796 | CDD:270678 | 121/324 (37%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||