Protein Alignment Src64B and zak-1

DIOPT Version :10

• Sequence 1: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001367790.1
• Gene: zak-1 / 175954
• WormBaseID: WBGene00006971
• Length: 745
• Species: Caenorhabditis elegans
• Alignment Length: 268
• Identity: 85/268 - (31%)
• Similarity: 134/268 - (50%)
• Gaps: 33/268 - (12%)

  Fly   279 EIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFL------QEAAIMKKFRH 337
            :|.|.:||:...:|.|.||.||.|.|         ||.:|:..|.|..      :||.|:.|.||
 Worm    25 DIQRDDIQVGDHIGVGTFGAVFSGNW---------TLPDGSQRTIALKKVFVLEKEAEILSKIRH 80

  Fly   338 NRLVALYAVC-SQEEPIYIVQEYMSKGSLLDFLREGDGRYL-------HFEDLIYIATQVASGME 394
            ..::..|.:| :.....:||.||..||||.||:...:.:..       .|:.::..|:|:|||::
 Worm    81 KNIIQFYGICKATGNDFFIVTEYAEKGSLYDFIHSEESQSFASSSGGNSFDVVVKWASQIASGIQ 145

  Fly   395 YLE---SKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYG 456
            ||.   ...:|||||.::||::.:|.|.||||||.::.:......|..|.  ...|.:||.|:..
 Worm   146 YLHYDAVDTIIHRDLKSKNVVLDKNLVCKICDFGTSKDLTHSCTAPSWGG--TAAWMSPEMILQS 208

  Fly   457 K-FSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENI-ERGFRMPKPTNHYFPDNIYQLLLQC 519
            : .:..:||||||::|.|:.: .:|||.......:...| :.|..:..|.:  .|..:.||:..|
 Worm   209 EGLTTATDVWSYGVVLWEILS-KEVPYKDYSEFRIFTMITQSGITLAIPPS--CPAPLKQLMSNC 270

  Fly   520 WDAVPEKR 527
            |...|:.|
 Worm   271 WKMTPKDR 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH2_Src_family	158..259	CDD:199827
		PTKc_Src_like	289..538	CDD:270630	81/258 (31%)
		SH3_Src_like	99..150	CDD:212779
zak-1	NP_001367790.1	Protein Kinases, catalytic domain	38..291	CDD:473864	81/255 (32%)