Protein Alignment Src64B and map3k9

DIOPT Version :10

• Sequence 1: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_002936940.2
• Gene: map3k9 / 100488949
• XenbaseID: XB-GENE-989075
• Length: 1104
• Species: Xenopus tropicalis
• Alignment Length: 582
• Identity: 144/582 - (24%)
• Similarity: 214/582 - (36%)
• Gaps: 186/582 - (31%)

  Fly    26 SDYTFGQTHINSSGGGNMGGVL-------GQKHNNGGSLDSR--YTPDPNHRGPLKIGGKGGVD- 80
            |..|||.    :.||||...:.       .::..:.||..:|  :..:.:.      ||..|.|
 Frog    14 SKTTFGA----NRGGGNASALPVPLVSEDDEEQEDRGSTPTRQDFVEEEDD------GGGSGKDA 68

  Fly    81 --IIRPRTTPTGVPGVVLKRVVVALYDYKSRDESDLSFMKGDRMEVIDDTES-----DWW----- 133
              |....::.|..|     ....|::||::..|.:|:...||.::|:....|     .||
 Frog    69 GFIAEQPSSSTSNP-----LYWTAVFDYEASAEDELTLRLGDLVQVLSKDSSVSGDEGWWTGKIQ 128

  Fly   134 -RVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNG 197
             ||        |:.|.|:|...:|.:|:
 Frog   129 DRV--------GIFPSNYVTRTQSFSSK------------------------------------- 148

  Fly   198 YSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKENALGLCHILSRPC-P 261
                           ::..|::.|                                     || |
 Frog   149 ---------------LQGKRVEEL-------------------------------------PCYP 161

  Fly   262 KPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREG-----TMS 321
            ....|:          .||..||:.|...:|.|.||:|:...|... :||||..|..     :.:
 Frog   162 ASALQL----------EEIDFSEMVLEEIIGIGGFGKVYRAIWGQE-EVAVKAARHDPDEDISQT 215

  Fly   322 TAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIA 386
            .....|||.:.....|..::||..||.:|..:.:|.|:...|||...|   .|:.:..:.|:..|
 Frog   216 IENVRQEAKLFAMLDHPNIIALRGVCLKEPNLCLVMEFARGGSLNRVL---SGKKIPPDILVNWA 277

  Fly   387 TQVASGMEYLESKQL---IHRDLAARNVLI------GE--NNVAKICDFGLARVIADDEYCPKQG 440
            .|:|.||.||.::.:   |||||.:.||||      |:  ..:.||.||||||   :.....|..
 Frog   278 VQIARGMNYLHNEAIVPVIHRDLKSSNVLILQMVENGDLSKKILKITDFGLAR---EWHRTTKMS 339

  Fly   441 SRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERG-FRMPKPT 504
            :.....|.|||.|....||..|||||||:||.||.| |:||:.|:....|...:... ..:|.|:
 Frog   340 AAGTYAWMAPEVIRSSMFSKGSDVWSYGVLLWELLT-GEVPFRGIDGLAVAYGVAMNKLSLPIPS 403

  Fly   505 NHYFPDNIYQLLLQCWDAVPEKRPTFE-------------FLNHYFESFSVTSEVPYREVQD 553
            .  .|:...:|:..||:..|..||.|.             |.....|||....|...||:|:
 Frog   404 T--CPEPFARLMEDCWNPDPHCRPPFTNILFQLTTIEESGFFEMPKESFHSLQEDWKREIQE 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH2_Src_family	158..259	CDD:199827	3/100 (3%)
		PTKc_Src_like	289..538	CDD:270630	89/278 (32%)
		SH3_Src_like	99..150	CDD:212779	15/61 (25%)
map3k9	XP_002936940.2	SH3_MLK1-3	84..141	CDD:212992	17/64 (27%)
		STKc_MLK1	168..437	CDD:271047	93/278 (33%)