Protein Alignment Src64B and map3k10

DIOPT Version :10

• Sequence 1: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_002938858.3
• Gene: map3k10 / 100488058
• XenbaseID: XB-GENE-920944
• Length: 990
• Species: Xenopus tropicalis
• Alignment Length: 452
• Identity: 118/452 - (26%)
• Similarity: 172/452 - (38%)
• Gaps: 141/452 - (31%)

  Fly   101 VALYDYKSRDESDLSFMKGDRMEVI--DDT---ESDWWRVVNLTTRQEGLIPLNFVAEERSVNSE 160
            :|::||::..|.:|:..:||.:|::  |.|   :..||  ......:.|:.|.|:|
 Frog    39 MAVFDYEATAEEELTLHRGDLVEILSKDSTVSGDEGWW--TGKIKDKVGIFPSNYV--------- 92

  Fly   161 DWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGG 225
                             ..:|...|....|.:
 Frog    93 -----------------VSDNKYTTLTGAPKQ--------------------------------- 107

  Fly   226 YYIATNQTFPSLQALVMAYSKENALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRK 290
                                              ||.|              .||...|:.|...
 Frog   108 ----------------------------------CPLP--------------LEIEFEELNLEEI 124

  Fly   291 LGRGNFGEVFYGKWRNSIDVAVKTLR----EGTMSTAAFL-QEAAIMKKFRHNRLVALYAVCSQE 350
            :|.|.||:|:.|.||.. :||||.:|    |....||..: |||.:.....|..::||..||.:.
 Frog   125 IGVGGFGKVYKGLWRGD-EVAVKAVRHDPDEDINVTAENVRQEAKLFCMLCHPNIIALKGVCLKP 188

  Fly   351 EPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESK---QLIHRDLAARNVL 412
            ..:.:|.||...|.|...|.   |:.:....|:..|.|:|.||.||.::   .:|||||.:.|:|
 Frog   189 PHLCLVMEYARGGPLHRALA---GKKVPAHVLVNWAVQIARGMNYLHNEAIVPIIHRDLKSSNIL 250

  Fly   413 IGE--------NNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGI 469
            |.|        |...||.||||||   :.:...|..:.....|.|||.|....||..|||||:|:
 Frog   251 ILEKVEHDDLFNKTLKITDFGLAR---EWQKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGV 312

  Fly   470 LLMELFTYGQVPYPGMHSREVIENIERG-FRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTF 530
            ||.||.| |:|||..:.:..|...:... ..:|.|:.  .|:...::|..|||..|..||:|
 Frog   313 LLWELLT-GEVPYREIDALAVAYGVAMNKLTLPIPST--CPEPFVRILEACWDPDPHSRPSF 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Src64B	NP_001286937.1	SH2_Src_family	158..259	CDD:199827	3/100 (3%)
		PTKc_Src_like	289..538	CDD:270630	92/259 (36%)
		SH3_Src_like	99..150	CDD:212779	14/53 (26%)
map3k10	XP_002938858.3	SH3_MLK1-3	37..94	CDD:212992	16/82 (20%)
		STKc_MLK2	124..381	CDD:271050	92/258 (36%)