DRSC/TRiP Functional Genomics Resources

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Protein Alignment Src64B and nck1b

DIOPT Version :10

Sequence 1:NP_001286937.1 Gene:Src64B / 48973 FlyBaseID:FBgn0262733 Length:553 Species:Drosophila melanogaster
Sequence 2:XP_002666641.1 Gene:nck1b / 100334953 ZFINID:ZDB-GENE-090317-1 Length:381 Species:Danio rerio


Alignment Length:174 Identity:50/174 - (28%)
Similarity:85/174 - (48%) Gaps:36/174 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   100 VVALYDYKSRDESDLSFMKGDRMEVIDDTESD--WWRVVNLTTRQEGLIPLNFVAE-ERSVNS-- 159
            |.|||.:.|.::.:|:|.||:.|:|::..|:|  ||: ...:..|.||:|.|:|.. :.|.||  
Zfish   196 VQALYPFSSGNDEELNFEKGEVMDVVEKPENDPEWWK-CRKSDGQMGLVPKNYVTVLQESHNSAS 259

  Fly   160 ----------------------EDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSV 202
                                  :.|::..|.|.:|: :.|.:....|.||:|.||.:||.:|:|:
Zfish   260 MPGPPTPDCDYIEPSSSGRFAGKQWYYGKVTRHQAE-VALNQRGSEGDFLIRDSESSPNDFSISL 323

  Fly   203 KDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSK 246
            |.....     ||::::..||  .|....:.|.:::.||..|.|
Zfish   324 KAQSKN-----KHFKVQLKDN--LYCIGQRKFNTMEELVEHYKK 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Src64BNP_001286937.1 SH2_Src_family 158..259 CDD:199827 28/113 (25%)
PTKc_Src_like 289..538 CDD:270630
SH3_Src_like 99..150 CDD:212779 19/51 (37%)
nck1bXP_002666641.1 SH3_Nck1_1 3..61 CDD:212833
SH3_Nck1_2 109..163 CDD:212834
SH3_Nck1_3 194..250 CDD:212837 21/54 (39%)
SH2 282..378 CDD:472789 26/87 (30%)
Blue background indicates that the domain is not in the aligned region.

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