Protein Alignment Atpalpha and atp1a1a.3

DIOPT Version :10

• Sequence 1: NP_732572.1
• Gene: Atpalpha / 48971
• FlyBaseID: FBgn0002921
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_571763.1
• Gene: atp1a1a.3 / 64614
• ZFINID: ZDB-GENE-001212-3
• Length: 1024
• Species: Danio rerio
• Alignment Length: 1029
• Identity: 744/1029 - (72%)
• Similarity: 878/1029 - (85%)
• Gaps: 12/1029 - (1%)

  Fly    13 DSYRVATVIATDDDNRTADGQYKSRRKMPAKVNKKENLDDLKQELDIDFHKISPEELYQRFQTHP 77
            |.|::|   ||.:     ||..|.::   .|.|||: :|:||:|:::|.||::.|||.:::.|..
Zfish     8 DEYKLA---ATSE-----DGVKKPKK---GKKNKKD-MDELKKEVEMDDHKLTLEELSRKYGTDL 60

  Fly    78 ENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGAILCFVAYSIQASTSEE 142
            ..|||..:|||.|.||||||||||..||||||||:.|||||..||||||:|||.||||||::.||
Zfish    61 NKGLSITRAKEILARDGPNALTPPVTTPEWVKFCRQLFGGFQTLLWIGALLCFFAYSIQAASEEE 125

  Fly   143 PADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGD 207
            ||:||||||:||:.||.|.|.||||||:|||:||:||:|:|||.|.|:|||||..:.|||:|:||
Zfish   126 PANDNLYLGLVLAFVVTVNGCFSYYQEAKSSRIMDSFRNLVPQKALVVREGEKSVIDAEDVVVGD 190

  Fly   208 VVEVKFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHENPLETKNLAFFSTNAVEGTA 272
            :||||.||||||||||:.::..||||||||||||||:|..|.:.:|||||:|:||||||.|:|.|
Zfish   191 LVEVKGGDRIPADIRIVSSQGCKVDNSSLTGESEPQTRAPEMSSDNPLETRNIAFFSTNCVDGAA 255

  Fly   273 KGVVISCGDHTVMGRIAGLASGLDTGETPIAKEIHHFIHLITGVAVFLGVTFFVIAFILGYHWLD 337
            :|||::.||.|||||||.|||.|:.|:||||:||.||||:|||||||||:||.|::.||||:||:
Zfish   256 RGVVVNTGDRTVMGRIASLASSLEGGQTPIAREIEHFIHIITGVAVFLGLTFLVLSLILGYNWLE 320

  Fly   338 AVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 402
            .||||||||||||||||.|||||||||||||||.|||||||||||||||||:|||||||||||||
Zfish   321 GVIFLIGIIVANVPEGLPATVTVCLTLTAKRMAKKNCLVKNLEAVETLGSTTTICSDKTGTLTQN 385

  Fly   403 RMTVAHMWFDNQIIEADTTEDQSGVQYDRTSPGFKALSRIATLCNRAEFKGGQDGVPILKKEVSG 467
            |||||||||||.|..|||||:|:|..:||:|..:.||:|:|.|||||.|:..|..:|:||::.:|
Zfish   386 RMTVAHMWFDNHIHIADTTENQTGASFDRSSATWSALARVAGLCNRAVFQSNQSHIPVLKRDTAG 450

  Fly   468 DASEAALLKCMELALGDVMNIRKRNKKIAEVPFNSTNKYQVSIHETEDTNDPRYLLVMKGAPERI 532
            ||||:|||||:||:.|.|..:|:...|:||:|||||||||||||:..::::|::|||||||||||
Zfish   451 DASESALLKCIELSCGSVAEMRENYTKLAEIPFNSTNKYQVSIHKNPNSSEPKHLLVMKGAPERI 515

  Fly   533 LERCSTIFINGKEKVLDEEMKEAFNNAYMELGGLGERVLGFCDFMLPSDKYPNGFKFNTDDINFP 597
            |||||||||.|||:.:|:|||:||.|||:|||||||||||||.|.||.|::|.||.|:|:::|||
Zfish   516 LERCSTIFIQGKEQPMDDEMKDAFQNAYLELGGLGERVLGFCHFCLPDDQFPEGFAFDTEEMNFP 580

  Fly   598 IDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNETVEDI 662
            .:||.|||||||||||||||||||||||||||||||||||||||||||||.|||||||||||:||
Zfish   581 TENLCFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVDDI 645

  Fly   663 AQRLNIPVSEVNPREAKAAVVHGAELRDVSSDQLDEILRYHTEIVFARTSPQQKLIIVEGCQRMG 727
            |.||.|.:.|||||:|||.|:||.||::::.:|||::|::|||||||||||||||||||||||.|
Zfish   646 AARLKIHIDEVNPRDAKACVIHGGELKNMTDEQLDDVLQHHTEIVFARTSPQQKLIIVEGCQRQG 710

  Fly   728 AIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKK 792
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   711 AIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKK 775

  Fly   793 SIAYTLTSNIPEISPFLAFILCDIPLPLGTVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDP 857
            ||||||||.|||:||||.|:|..||||||||||||||||||||||||||||.||:|||||.||:.
Zfish   776 SIAYTLTSKIPEMSPFLMFVLVGIPLPLGTVTILCIDLGTDMVPAISLAYETAESDIMKRQPRNA 840

  Fly   858 FNDKLVNSRLISMAYGQIGMIQAAAGFFVYFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDSYGQ 922
            ..|:|||.||||::|||||||||..|||.||||:|||||||..|.|||..|:.:.:|||.|||||
Zfish   841 ATDRLVNERLISVSYGQIGMIQAVGGFFTYFVILAENGFLPYDLVGIRVGWEDRFLNDLEDSYGQ 905

  Fly   923 EWTYRDRKTLEYTCHTAFFISIVVVQWADLIICKTRRNSIFQQGMRNWALNFGLVFETVLAAFLS 987
            :|||..||.:|||||||||.|||:|||.||:||||||.|||||||:|..|.|||:.||.||||||
Zfish   906 QWTYESRKIVEYTCHTAFFASIVIVQWTDLLICKTRRLSIFQQGMKNRVLTFGLLEETALAAFLS 970

  Fly   988 YCPGMEKGLRMYPLKLVWWFPAIPFALAIFIYDETRRFYLRRNPGGWLEQETYY 1041
            ||||||..:||||||.:|||.|.|::|.||||||.|::.||||||||:|:||||
Zfish   971 YCPGMEVAVRMYPLKPLWWFCAFPYSLLIFIYDEVRKYILRRNPGGWVERETYY 1024

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atpalpha	NP_732572.1	ATPase-IIC_X-K	45..1041	CDD:273445	733/995 (74%)
atp1a1a.3	NP_571763.1	ATPase-IIC_X-K	32..1024	CDD:273445	730/992 (74%)