DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mtr4 and AT3G46960

DIOPT Version :9

Sequence 1:	NP_524929.1	Gene:	Mtr4 / 48782	FlyBaseID:	FBgn0001986	Length:	1055	Species:	Drosophila melanogaster
Sequence 2:	NP_190280.5	Gene:	AT3G46960 / 823849	AraportID:	AT3G46960	Length:	1347	Species:	Arabidopsis thaliana

Alignment Length:	1200	Identity:	398/1200 - (33%)
Similarity:	603/1200 - (50%)	Gaps:	223/1200 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PPALNQ-----------------EEKPSGSSASKKGNKR---------------------QADGT 45
            ||:..|                 |:..|..:||.:.:.:                     :.|..
plant   205 PPSFKQSLDLGDLMPYPQTWSVYEDHSSHGNASDENSSKLSIQFDDLFKKAWEEDTFSELEGDDH 269

  Fly    46 TASKEATSSKGAEGDDKGDVTEEPTKRLKQEASTVAVDDDNNADDEPTRTLDIDDSATLEALRTR 110
            ||..|:..:: ||.|.|..::.|.:|.|:.:.:.:         ||      |..||....:...
plant   270 TAGSESPKAE-AEPDAKASISNEVSKGLETDVTVL---------DE------ILSSAKTAIMSEE 318

  Fly   111 IVTHLLD--------APKSCTHEVAAHPDQEYIPLKPFSGVPAKEYPFVLDPFQRQAILCIDNSQ 167
            .||...|        |.|..:.::|    ..:..|.|...:   |:||.||.||::||.|::..:
plant   319 AVTGSSDKQLRKEGWATKGDSQDIA----DRFYELVPDMAI---EFPFELDNFQKEAICCLEKGE 376

  Fly   168 SVLVSAHTSAGKTVVAEYAIAKSLAAKQ--RVIYTTPIKALSNQKFREFTDEFKDVGLVTGDVTI 230
            ||.|:||||||||||||||.|  ||.|.  |.:||.|||.:||||:|:|..:| ||||:||||:|
plant   377 SVFVAAHTSAGKTVVAEYAFA--LATKHCTRAVYTAPIKTISNQKYRDFCGKF-DVGLLTGDVSI 438

  Fly   231 NPSASCLIMTTEILRNMLYRGSEIMREVGWVVFDEIHYMRDKERGVVWEETLILLPDNVRYVFLS 295
            .|.||||||||||||:|||||::|:|::.||:|||:||:.|.||||||||.:|:||.::.:|.||
plant   439 RPEASCLIMTTEILRSMLYRGADIIRDIEWVIFDEVHYVNDVERGVVWEEVIIMLPRHINFVLLS 503

  Fly   296 ATIPNARQFAEWVCHLHKQPCHVVYTDYRPTPLQHYIFPAG------GDGIHL---IVDEKGQFK 351
            ||:||..:||:|:....::...|..|..||.||:|.:|.:|      .:.:.|   |.|.|...|
plant   504 ATVPNTFEFADWIGRTKQKEIRVTGTTKRPVPLEHCLFYSGELYKVCENEVFLSKGIKDAKDSQK 568

  Fly   352 EDNFTTAMAVL------ANAGEAGKGDQK---------GRHGGIKGT-------NAGQTNIFK-- 392
            :.| :.|::|.      ::|.:.|...||         .:|..:|..       |:.....|:
plant   569 KKN-SNAVSVAPKQQMGSSAHQDGSKSQKHEAHSRGKQNKHSSVKDVGKSSYSGNSQNNGAFRRS 632

  Fly   393 -------IVKMIMERNFAPVIIFSFSKKDCEIYAMQMAKLDFNTPDEKKLVDEVFNNAMDVLTEE 450
                   ::..:.:.:..||::|.|||..|:..|..:...|..:..||..:....:.|...|...
plant   633 AASNWLLLINKLSKMSLLPVVVFCFSKNYCDRCADALTGTDLTSSSEKSEIRVFCDKAFSRLKGS 697

  Fly   451 DRRLPQVENVLPLLRRGIGIHHGGLLPILKETIEILFGEGLIKALFATETFAMGLNMPARTVLFT 515
            ||.||||..:..||.||||:||.|||||:||.:|:||..|:||.||:|||||||:|.|||||:|.
plant   698 DRNLPQVLRLQSLLHRGIGVHHAGLLPIVKEVVEMLFCRGVIKVLFSTETFAMGVNAPARTVVFD 762

  Fly   516 APRKFDGKKFRWISSGEYIQMAGRAGRRGLDDKGIVILMI-DEKVSPAVGRDIVQGKADPINSAF 579
            |.||||||:||.:..|||.||||||||||||..|.|::|. ||....:..|.::.|.|..:.|.|
plant   763 ALRKFDGKEFRQLLPGEYTQMAGRAGRRGLDKTGTVVVMCRDEVPDESDLRRVIVGSATRLESQF 827

  Fly   580 HLTYNMVLNLLRVEEINPEYMLERSFYQFQNQAALPGLHDQVEQKTLELNKLT--------IKDE 636
            .|||.|:|:||||||:..|.||:|||.:|..|..||      |::.|.:.|.:        ||.|
plant   828 RLTYIMILHLLRVEELKVEDMLKRSFAEFHAQKKLP------EKQQLLMIKRSLPTKHIECIKGE 886

  Fly   637 HNIASYHHIRSQLDQHGKQFRQWITKPQYLLPFLQPGRLVKVAAG-------------------- 681
            ..|..|:.:..:.:::..:..:.:.:..|...||..||:|.:.:|
plant   887 PAIEDYYDMYMEANEYNNKMSEAVMQSPYAQSFLVQGRVVVMKSGMGIDNLLGIVLKGPSNTNRQ 951

  Fly   682 ---------------------------SQEY------DWGIVLNFKKQDQSRKNPLKAEPSVTID 713
                                       ||.|      ..|....|..:..|||.|      |.|.
plant   952 YVVLVIKSEIPPPEKNMVSIGKKSSDPSQGYFIAPKSKRGFEEEFYTKPSSRKGP------VVIK 1010

  Fly   714 VLLHVSEAAAKTGDTEPCKPNERGCMEVVPVAHTLITQISSIRVYFPNDLRSADNRRAVLKTIQE 778
            :.|.....||..|.......|:    |.:.:..:.| :|..:|      |....|:.|..:|:|:
plant  1011 IELPYHGVAAGVGYEVKGFDNK----EFLCICDSKI-KIDQVR------LLEDGNKAAFSQTVQQ 1064

  Fly   779 A------KKRFPLGPPVLNPIDDMNIKDREFRDIVNTISQFEKRLEEHPLHKSPELERIHRRYQD 837
            .      ..:|   ||.|:|:.|:.:||.|   :|.|..::...|::..::|.....::    ::
plant  1065 LLDLKSDGNKF---PPALDPVKDLKLKDAE---LVETYYKWTNLLQKMSMNKCHGCVKL----EE 1119

  Fly   838 KVTLQKQLQDLKAELK------AARSLLQMDELKHRKRVLRRMGYCKPGDVIEFKGRVACELSSA 896
            .:.|.::::..|.:||      :..:||||...:.|..||:.:|......|::.|||||||::|.
plant  1120 HMKLAREIKKHKTDLKDLEFQMSDEALLQMPAFQGRIDVLKNIGCIDDDLVVQIKGRVACEMNSG 1184

  Fly   897 DELLMTEMIFNGVFNDLTAPQAVALLSCFVCDEKSSESVKSATELSGPLRSMQDLARRIAKVSTE 961
            :||:.|..:|...|.:|...:|||::|.||..:|::.:.....:|:...:.:.|.|.|:.::..:
plant  1185 EELICTVCLFENQFEELEPEEAVAIMSAFVFQQKNTSAPTLTPKLAKAKQRLYDTAIRLGELQAQ 1249

  Fly   962 CKLDLDADTYVDKFKPF-LMDVVLAWCKGSSFLAVCKMTDIFEGSIIRCMRRLEELLRQMCQASK 1025
            ..|.:|.:.|..:...| |::||..|.||:.|..:|::||:.||.|:|.:.||:|..|:...|:.
plant  1250 YNLQIDPEEYAQENLKFGLVEVVYEWAKGTPFAEICELTDVPEGLIVRTIVRLDETCREFKNAAA 1314

  Fly  1026 TIGNTDLENKFSEGIRLLKRDIVFAASLYL 1055
            .:||:.|..|.......:|||||||||||:
plant  1315 IMGNSALHKKMDAASNAIKRDIVFAASLYV 1344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtr4	NP_524929.1	Dob10	91..1055	CDD:226947	378/1088 (35%)
		DEAD	154..299	CDD:278688	92/146 (63%)
		HELICc	390..554	CDD:238034	83/172 (48%)
		rRNA_proc-arch	600..853	CDD:289976	64/319 (20%)
		DSHCT	881..1048	CDD:285374	56/167 (34%)
AT3G46960	NP_190280.5	Dob10	264..1343	CDD:226947	389/1138 (34%)
		DEAD	365..509	CDD:278688	92/146 (63%)
		HELICc	711..791	CDD:197757	56/79 (71%)
		rRNA_proc-arch	848..1142	CDD:289976	66/326 (20%)
		DSHCT	1169..1337	CDD:285374	56/167 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	203	1.000	Domainoid score	I840
eggNOG	1	0.900	-	-		E1_COG4581
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D176060at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100340
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.720