Protein Alignment Mtr4 and mtrex

DIOPT Version :10

• Sequence 1: NP_524929.1
• Gene: Mtr4 / 48782
• FlyBaseID: FBgn0001986
• Length: 1055
• Species: Drosophila melanogaster
• Sequence 2: NP_999933.1
• Gene: mtrex / 406795
• ZFINID: ZDB-GENE-040426-2854
• Length: 1034
• Species: Danio rerio
• Alignment Length: 1067
• Identity: 661/1067 - (61%)
• Similarity: 814/1067 - (76%)
• Gaps: 54/1067 - (5%)

  Fly     4 EELFDCFDEVTPSVPPPALNQEEKPSGSSASKKGNKRQADGTTASKEATSSKGAEGDDKGDVTEE 68
            ::||..|||........|..:....:|.:..|.| |.|.|..:..|.       :.||.|
Zfish     7 DDLFSVFDEEQAGSSKKAAPKSAANAGKTPDKAG-KPQGDSASLRKR-------DADDDG----- 58

  Fly    69 PTKRL---KQEASTVAVDDDNNADDEPTRTLDIDDSATLEALRTRIVTHLLDAPKSCTHEVAAHP 130
            |.:.|   :|:..||:.::.|                 |..|..::.:..::..:.|||||....
Zfish    59 PDEMLLGKRQKLETVSAEEIN-----------------LSELMPKVKSEQVETVEGCTHEVVLPA 106

  Fly   131 DQEYIPLKPFSGVPAKEYPFVLDPFQRQAILCIDNSQSVLVSAHTSAGKTVVAEYAIAKSLAAKQ 195
            ::||.||||..|..||||||:||||||:|||||||:|||||||||||||||.||||||.:|..||
Zfish   107 NEEYTPLKPRVGKAAKEYPFILDPFQREAILCIDNNQSVLVSAHTSAGKTVCAEYAIALALREKQ 171

  Fly   196 RVIYTTPIKALSNQKFREFTDEFKDVGLVTGDVTINPSASCLIMTTEILRNMLYRGSEIMREVGW 260
            |||:|:|||||||||:||..:||:||||:||||||||:||||:|||||||:|||||||:||||.|
Zfish   172 RVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAW 236

  Fly   261 VVFDEIHYMRDKERGVVWEETLILLPDNVRYVFLSATIPNARQFAEWVCHLHKQPCHVVYTDYRP 325
            |:|||||||||.|||||||||:|||||||.:||||||:|||||||||:|||||||||||||||||
Zfish   237 VIFDEIHYMRDSERGVVWEETIILLPDNVHHVFLSATVPNARQFAEWICHLHKQPCHVVYTDYRP 301

  Fly   326 TPLQHYIFPAGGDGIHLIVDEKGQFKEDNFTTAMAVLANAGEAG-----KGDQKGRHGGIKGTNA 385
            ||||||||||||||:||:|||.|:|:||||.|||.||.:||:.|     |.|.|||.||.|
Zfish   302 TPLQHYIFPAGGDGLHLVVDENGEFREDNFNTAMQVLRDAGDTGGNTGAKWDPKGRKGGTK---- 362

  Fly   386 GQTNIFKIVKMIMERNFAPVIIFSFSKKDCEIYAMQMAKLDFNTPDEKKLVDEVFNNAMDVLTEE 450
            |.:|:||||||||||||.||||||||||:||.||:|::||||||.:|||||:||||||.|.|::|
Zfish   363 GPSNVFKIVKMIMERNFQPVIIFSFSKKECEAYALQVSKLDFNTDEEKKLVEEVFNNATDCLSDE 427

  Fly   451 DRRLPQVENVLPLLRRGIGIHHGGLLPILKETIEILFGEGLIKALFATETFAMGLNMPARTVLFT 515
            |::|||||:|||||:||||||||||||||||||||||.|||:||||||||||||:||||||||||
Zfish   428 DKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLLKALFATETFAMGINMPARTVLFT 492

  Fly   516 APRKFDGKKFRWISSGEYIQMAGRAGRRGLDDKGIVILMIDEKVSPAVGRDIVQGKADPINSAFH 580
            :.||||||.||||||||||||:|||||||:|::||||.|:|||:|||||:.:::|.|||:|||||
Zfish   493 SARKFDGKDFRWISSGEYIQMSGRAGRRGMDERGIVIFMVDEKMSPAVGKQLLKGSADPLNSAFH 557

  Fly   581 LTYNMVLNLLRVEEINPEYMLERSFYQFQNQAALPGLHDQVEQKTLELNKLTIKDEHNIASYHHI 645
            ||||||||||||||||||||||:||||||:..|:||:.|::::...|.|.:.|..|.::.:|:.|
Zfish   558 LTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAVPGVVDRMKKLEEEYNAIRIPKEESVVTYYKI 622

  Fly   646 RSQLDQHGKQFRQWITKPQYLLPFLQPGRLVKVAAGSQEYDWGIVLNFKKQDQSRKNPLKA---- 706
            |.||.:.||:..::|.||:|.||||||||||||.....::.||:|:||:|     |:.:||
Zfish   623 RQQLAKLGKEIEEFIHKPRYCLPFLQPGRLVKVKKEDLDFGWGVVVNFQK-----KSNVKAGGDL 682

  Fly   707 EPSVTIDVLLHVSEAAAKTGDTE---PCKPNERGCMEVVPVAHTLITQISSIRVYFPNDLRSADN 768
            :|...::||:|.|:.:.|...||   |..|.|:|.|:||||...|||.|||:|:|.|.|||..||
Zfish   683 DPLFVVEVLVHCSKDSVKNAATESARPAGPAEKGEMQVVPVILHLITSISSVRLYIPKDLRPYDN 747

  Fly   769 RRAVLKTIQEAKKRFPLGPPVLNPIDDMNIKDREFRDIVNTISQFEKRLEEHPLHKSPELERIHR 833
            |:::||:|||.:||||.|.|:|:|||||.|||...:.::..:..||.|:..||||..|.||.:::
Zfish   748 RQSMLKSIQEVQKRFPDGIPLLDPIDDMGIKDPALKKVIQKVEAFEHRMYTHPLHSDPNLEAVYK 812

  Fly   834 RYQDKVTLQKQLQDLKAELKAARSLLQMDELKHRKRVLRRMGYCKPGDVIEFKGRVACELSSADE 898
            ..:.|..:...::..|.|||.||::|||||||.|||||||:|:....||||.|||||||.||.||
Zfish   813 LCEKKALIAGDIKAAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACETSSGDE 877

  Fly   899 LLMTEMIFNGVFNDLTAPQAVALLSCFVCDEKSSESVKSATELSGPLRSMQDLARRIAKVSTECK 963
            ||:|||:|||:||||||.||.|||||||..|.::|..|...:|.||||.||:.|:||||||.|.|
Zfish   878 LLLTEMMFNGLFNDLTAEQATALLSCFVFQENANEMPKLTEQLGGPLRQMQECAKRIAKVSAEAK 942

  Fly   964 LDLDADTYVDKFKPFLMDVVLAWCKGSSFLAVCKMTDIFEGSIIRCMRRLEELLRQMCQASKTIG 1028
            |::|.|:|:::|:|.|||||..|..||||..:|||||:||||||||||||||||||||||:|.||
Zfish   943 LEVDEDSYLNQFRPHLMDVVYTWANGSSFSQICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIG 1007

  Fly  1029 NTDLENKFSEGIRLLKRDIVFAASLYL 1055
            ||:|||||:.||..:||||||||||||
Zfish  1008 NTELENKFATGITKIKRDIVFAASLYL 1034

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtr4	NP_524929.1	Dob10	145..1048	CDD:443638	616/914 (67%)
mtrex	NP_999933.1	Dob10	115..1006	CDD:443638	604/899 (67%)