Protein Alignment Mtr4 and Mtrex

DIOPT Version :10

• Sequence 1: NP_524929.1
• Gene: Mtr4 / 48782
• FlyBaseID: FBgn0001986
• Length: 1055
• Species: Drosophila melanogaster
• Sequence 2: NP_001029265.1
• Gene: Mtrex / 365668
• RGDID: 1305984
• Length: 1042
• Species: Rattus norvegicus
• Alignment Length: 1067
• Identity: 668/1067 - (62%)
• Similarity: 820/1067 - (76%)
• Gaps: 46/1067 - (4%)

  Fly     4 EELFDCF-DEVTPSVPPPALNQEEK-----PSGSSASKKGNKRQADGTTASKEATSSKGAEGDDK 62
            :|||..| |:.|.:.......::||     |.| .|.|.|  ::.|....|:.|:|     |.:|
  Rat     7 DELFSVFEDDSTTAAGTKKDKEKEKDKWKGPPG-PADKAG--KRLDTRLQSEPASS-----GKNK 63

  Fly    63 GDVTEEPTKRLKQEASTVAVDDDNNADDEP-----TRTLD-IDDSATLEALRTRIVTHLLDAPKS 121
            .|:..|.|                   |||     .|..| |::..:|..|..|:....::..:.
  Rat    64 RDLDVEGT-------------------DEPIFGKKPRIEDSINEDLSLADLMPRVKVQSVETVEG 109

  Fly   122 CTHEVAAHPDQEYIPLKPFSGVPAKEYPFVLDPFQRQAILCIDNSQSVLVSAHTSAGKTVVAEYA 186
            ||||||...|::||||||..|..||||||:||.|||:||.|:||:|||||||||||||||.||||
  Rat   110 CTHEVALPADEDYIPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYA 174

  Fly   187 IAKSLAAKQRVIYTTPIKALSNQKFREFTDEFKDVGLVTGDVTINPSASCLIMTTEILRNMLYRG 251
            ||.:|..|||||:|:|||||||||:||..:||:||||:||||||||:||||:|||||||:|||||
  Rat   175 IALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRG 239

  Fly   252 SEIMREVGWVVFDEIHYMRDKERGVVWEETLILLPDNVRYVFLSATIPNARQFAEWVCHLHKQPC 316
            ||:||||.||:|||||||||.|||||||||:|||||||.|||||||||||||||||:||||||||
  Rat   240 SEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPC 304

  Fly   317 HVVYTDYRPTPLQHYIFPAGGDGIHLIVDEKGQFKEDNFTTAMAVLANAGEAGKGDQKGRHGGIK 381
            ||:||||||||||||||||||||:||:|||.|.|:||||.|||.||.:||:..|||||||.||.|
  Rat   305 HVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTK 369

  Fly   382 GTNAGQTNIFKIVKMIMERNFAPVIIFSFSKKDCEIYAMQMAKLDFNTPDEKKLVDEVFNNAMDV 446
                |.:|:||||||||||||.|||||||||||||.||:||.||||||.:|||:|:||||||:|.
  Rat   370 ----GPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFNNAIDC 430

  Fly   447 LTEEDRRLPQVENVLPLLRRGIGIHHGGLLPILKETIEILFGEGLIKALFATETFAMGLNMPART 511
            |::||::|||||:|||||:||||||||||||||||||||||.||||||||||||||||:||||||
  Rat   431 LSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPART 495

  Fly   512 VLFTAPRKFDGKKFRWISSGEYIQMAGRAGRRGLDDKGIVILMIDEKVSPAVGRDIVQGKADPIN 576
            ||||..||:|||.||||||||||||:|||||||:||:||||||:|||:||.:|:.:::|.|||:|
  Rat   496 VLFTNARKYDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLN 560

  Fly   577 SAFHLTYNMVLNLLRVEEINPEYMLERSFYQFQNQAALPGLHDQVEQKTLELNKLTIKDEHNIAS 641
            ||||||||||||||||||||||||||:||||||:..|:||:.::|:....:.||:.|.:|.|:..
  Rat   561 SAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEENVVI 625

  Fly   642 YHHIRSQLDQHGKQFRQWITKPQYLLPFLQPGRLVKVAAGSQEYDWGIVLNFKKQDQSRKNPLKA 706
            |:.||.||.:.||:..::|.||:|.||||||||||||.....::.||:|:||.|:...:.|..:.
  Rat   626 YYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGEL 690

  Fly   707 EPSVTIDVLLHVSEAAAKTGDTE---PCKPNERGCMEVVPVAHTLITQISSIRVYFPNDLRSADN 768
            :|...::|||..|:.:.|...||   |.||:|:|.|:||||...|::.||::|:|.|.|||..||
  Rat   691 DPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISTVRLYIPKDLRPVDN 755

  Fly   769 RRAVLKTIQEAKKRFPLGPPVLNPIDDMNIKDREFRDIVNTISQFEKRLEEHPLHKSPELERIHR 833
            |::|||:|||.:||||.|.|:|:|||||.|:|:..:.::..:..||.|:..||||..|.||.::.
  Rat   756 RQSVLKSIQEVQKRFPDGVPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYT 820

  Fly   834 RYQDKVTLQKQLQDLKAELKAARSLLQMDELKHRKRVLRRMGYCKPGDVIEFKGRVACELSSADE 898
            ..:.|..:...::..|.|||.||::|||||||.|||||||:|:....||||.|||||||:|||||
  Rat   821 LCEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADE 885

  Fly   899 LLMTEMIFNGVFNDLTAPQAVALLSCFVCDEKSSESVKSATELSGPLRSMQDLARRIAKVSTECK 963
            ||:|||:|||:||||::.||.|||||||..|.|||..|...:|:||||.||:.|:||||||.|.|
  Rat   886 LLLTEMMFNGLFNDLSSEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAK 950

  Fly   964 LDLDADTYVDKFKPFLMDVVLAWCKGSSFLAVCKMTDIFEGSIIRCMRRLEELLRQMCQASKTIG 1028
            |::|.:||:..|||.|||||..|..|::|..:|||||:||||||||||||||||||||||:|.||
  Rat   951 LEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIG 1015

  Fly  1029 NTDLENKFSEGIRLLKRDIVFAASLYL 1055
            ||:|||||:|||..:||||||||||||
  Rat  1016 NTELENKFAEGITKIKRDIVFAASLYL 1042

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtr4	NP_524929.1	Dob10	145..1048	CDD:443638	614/905 (68%)
Mtrex	NP_001029265.1	Dob10	127..1014	CDD:443638	601/890 (68%)